New Constituents of Artemisia monosperma

Michael Stavri, K. Thomas Mathew, Trevor Gibson, R. Thomas Williamson, Simon Gibbons

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Abstract

A new eudesmane sesquiterpene (1) and a C10 diyne (2) were isolated from the aerial parts of Artemisia monosperma. The structures of these compounds were determined as rel-1β,3α,6β-trihydroxyeudesm-4-ene (1) and 1,3R,8R-trihydroxydec-9-en-4,6-yne (2) on the basis of spectral data interpretation. The absolute stereochemistry of 2 was determined using Mosher ester methodology in which the terminal primary hydroxyl group was first protected to simplify the stereochemical analysis.
Original languageEnglish
Pages (from-to)892-894
Number of pages3
JournalJournal of Natural Products
Volume67
Issue number5
DOIs
Publication statusPublished - 1 May 2004

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