New pacidamycins biosynthetically: probing N- and C-terminal substrate specificity of an unusual NRPS

Amany E. Ragab, Sabine Gruschow, Emma J. Rackham, Rebecca J. M. Goss

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

Feeding phenylalanine analogues to Streptomyces coeruleorubidus reveals the remarkable steric and electronic flexibility of this biosynthetic pathway and leads to the generation of a series of new halopacidamycins.
Original languageEnglish
Pages (from-to)3128-3129
Number of pages2
JournalOrganic & Biomolecular Chemistry
Volume8
Issue number14
DOIs
Publication statusPublished - 2010

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