Nonsurgical reduction of the interventricular septum in patients with hypertrophic cardiomyopathy

Waqar Shamim, Mohammed Yousufuddin, Duolao Wang, Michael Henein, Hubert Seggewiss, Marcus Flather, Andrew J S Coats, Ulrich Sigwart

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49 Citations (Scopus)


In patients with hypertrophic cardiomyopathy and obstruction of the left ventricular outflow tract, nonsurgical reduction of the septum is a treatment option when medical therapy has failed. We investigated the long-term effects of nonsurgical reduction of the septum on functional capacity and electrocardiographic and echocardiographic characteristics.
Original languageEnglish
Pages (from-to)1326-33
Number of pages8
JournalNew England Journal of Medicine
Issue number17
Publication statusPublished - 24 Oct 2002


  • Analysis of Variance
  • Cardiomyopathy, Hypertrophic
  • Echocardiography, Stress
  • Electrocardiography
  • Ethanol
  • Exercise Test
  • Exercise Tolerance
  • Female
  • Follow-Up Studies
  • Heart Block
  • Heart Septum
  • Humans
  • Injections
  • Male
  • Middle Aged
  • Myocardial Infarction
  • Treatment Outcome

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