Nonsurgical reduction of the interventricular septum in patients with hypertrophic cardiomyopathy

Waqar Shamim; Mohammed Yousufuddin; Duolao Wang; Michael Henein; Hubert Seggewiss; Marcus Flather; Andrew J S Coats; Ulrich Sigwart

doi:10.1056/NEJMoa012710

Nonsurgical reduction of the interventricular septum in patients with hypertrophic cardiomyopathy

Waqar Shamim, Mohammed Yousufuddin, Duolao Wang, Michael Henein, Hubert Seggewiss, Marcus Flather, Andrew J S Coats, Ulrich Sigwart

Research output: Contribution to journal › Article › peer-review

50 Citations (Scopus)

Abstract

In patients with hypertrophic cardiomyopathy and obstruction of the left ventricular outflow tract, nonsurgical reduction of the septum is a treatment option when medical therapy has failed. We investigated the long-term effects of nonsurgical reduction of the septum on functional capacity and electrocardiographic and echocardiographic characteristics.

Original language	English
Pages (from-to)	1326-33
Number of pages	8
Journal	New England Journal of Medicine
Volume	347
Issue number	17
DOIs	https://doi.org/10.1056/NEJMoa012710
Publication status	Published - 24 Oct 2002

Keywords

Analysis of Variance
Cardiomyopathy, Hypertrophic
Echocardiography, Stress
Electrocardiography
Ethanol
Exercise Test
Exercise Tolerance
Female
Follow-Up Studies
Heart Block
Heart Septum
Humans
Injections
Male
Middle Aged
Myocardial Infarction
Treatment Outcome

Access to Document

10.1056/NEJMoa012710

Cite this

@article{a7102938810841bcaeabb7e2bcd13685,

title = "Nonsurgical reduction of the interventricular septum in patients with hypertrophic cardiomyopathy",

abstract = "In patients with hypertrophic cardiomyopathy and obstruction of the left ventricular outflow tract, nonsurgical reduction of the septum is a treatment option when medical therapy has failed. We investigated the long-term effects of nonsurgical reduction of the septum on functional capacity and electrocardiographic and echocardiographic characteristics.",

keywords = "Analysis of Variance, Cardiomyopathy, Hypertrophic, Echocardiography, Stress, Electrocardiography, Ethanol, Exercise Test, Exercise Tolerance, Female, Follow-Up Studies, Heart Block, Heart Septum, Humans, Injections, Male, Middle Aged, Myocardial Infarction, Treatment Outcome",

author = "Waqar Shamim and Mohammed Yousufuddin and Duolao Wang and Michael Henein and Hubert Seggewiss and Marcus Flather and Coats, {Andrew J S} and Ulrich Sigwart",

year = "2002",

month = oct,

day = "24",

doi = "10.1056/NEJMoa012710",

language = "English",

volume = "347",

pages = "1326--33",

journal = "New England Journal of Medicine",

issn = "0028-4793",

publisher = "Massachussetts Medical Society",

number = "17",

}

TY - JOUR

T1 - Nonsurgical reduction of the interventricular septum in patients with hypertrophic cardiomyopathy

AU - Shamim, Waqar

AU - Yousufuddin, Mohammed

AU - Wang, Duolao

AU - Henein, Michael

AU - Seggewiss, Hubert

AU - Flather, Marcus

AU - Coats, Andrew J S

AU - Sigwart, Ulrich

PY - 2002/10/24

Y1 - 2002/10/24

N2 - In patients with hypertrophic cardiomyopathy and obstruction of the left ventricular outflow tract, nonsurgical reduction of the septum is a treatment option when medical therapy has failed. We investigated the long-term effects of nonsurgical reduction of the septum on functional capacity and electrocardiographic and echocardiographic characteristics.

AB - In patients with hypertrophic cardiomyopathy and obstruction of the left ventricular outflow tract, nonsurgical reduction of the septum is a treatment option when medical therapy has failed. We investigated the long-term effects of nonsurgical reduction of the septum on functional capacity and electrocardiographic and echocardiographic characteristics.

KW - Analysis of Variance

KW - Cardiomyopathy, Hypertrophic

KW - Echocardiography, Stress

KW - Electrocardiography

KW - Ethanol

KW - Exercise Test

KW - Exercise Tolerance

KW - Female

KW - Follow-Up Studies

KW - Heart Block

KW - Heart Septum

KW - Humans

KW - Injections

KW - Male

KW - Middle Aged

KW - Myocardial Infarction

KW - Treatment Outcome

U2 - 10.1056/NEJMoa012710

DO - 10.1056/NEJMoa012710

M3 - Article

C2 - 12397190

VL - 347

SP - 1326

EP - 1333

JO - New England Journal of Medicine

JF - New England Journal of Medicine

SN - 0028-4793

IS - 17

ER -