Normal Modes and Essential Dynamics

Steven Hayward; Bert L. de Groot

doi:10.1007/978-1-59745-177-2_5

Normal Modes and Essential Dynamics

Steven Hayward, Bert L. de Groot

Research output: Chapter in Book/Report/Conference proceeding › Chapter

117 Citations (Scopus)

Abstract

Normal mode analysis and essential dynamics analysis are powerful methods used for the analysis of collective motions in biomolecules. Their application has led to an appreciation of the importance of protein dynamics in function and the relationship between structure and dynamical behavior. In this chapter, the methods and their implementation are introduced and recent developments such as elastic networks and advanced sampling techniques are described.

Original language	English
Title of host publication	Molecular Modeling of Proteins
Editors	John M. Walker, Andreas Kukol
Publisher	The Humana Press Inc, USA
Pages	89-106
Number of pages	18
Volume	443
ISBN (Print)	978-1-59745-177-2
DOIs	https://doi.org/10.1007/978-1-59745-177-2_5
Publication status	Published - 2008

Publication series

Name	Methods in Molecular Biology
Publisher	The Humana Press Inc, USA

Access to Document

10.1007/978-1-59745-177-2_5

Cite this

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AB - Normal mode analysis and essential dynamics analysis are powerful methods used for the analysis of collective motions in biomolecules. Their application has led to an appreciation of the importance of protein dynamics in function and the relationship between structure and dynamical behavior. In this chapter, the methods and their implementation are introduced and recent developments such as elastic networks and advanced sampling techniques are described.

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T3 - Methods in Molecular Biology

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BT - Molecular Modeling of Proteins

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