Epilepsy is the most common chronic neurological condition, with antiepileptic drugs (AEDs) the cornerstone of therapy. Satisfaction with information received about therapy is associated with the extent to which patients understand and adhere to prescribed regimens. A National Society for Epilepsy (NSE) postal survey of its members (n = 197) reported that 50% of respondents did not feel that they were consistently provided with sufficient information about their condition or therapy. Regular reviews with the prescriber have been included into the general medical services contract as a part of the Quality and Outcomes Framework; however, a NSE-commissioned survey of general practitioners, reported that 21% of the 202 respondents would only conduct an epilepsy review if the patient presented for another condition. With a view to expanding the role of the community pharmacist, this study was designed to determine the effect of a pharmacist-led epilepsy clinic on patient satisfaction with information and mental well-being.