Notes on the practical utility of OPLS

Henri S. Tapp, E. Kate Kemsley

Research output: Contribution to journalReview articlepeer-review

37 Citations (Scopus)


This article concerns two chemometric modeling methods - the well-known partial least squares regression and the comparatively recently-devised orthogonal projections to latent structures (OPLS). We discuss their similarities and differences with a focus on the usage of OPLS in the analytical-chemistry literature. (C) 2009 Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)1322-1327
Number of pages6
JournalTrAC Trends in Analytical Chemistry
Issue number11
Publication statusPublished - Dec 2009


  • Partial least squares, PLS
  • Orthogonal projections to latent structures, OPLS
  • Performance equivalence
  • Interpretation
  • Correlation
  • Covariance

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