Nutrigenomics: goals and strategies

Michael Müller, Sander Kersten

Research output: Contribution to journalArticlepeer-review

476 Citations (Scopus)

Abstract

Nutrigenomics is the application of high-throughput genomics tools in nutrition research. Applied wisely, it will promote an increased understanding of how nutrition influences metabolic pathways and homeostatic control, how this regulation is disturbed in the early phase of a diet-related disease and to what extent individual sensitizing genotypes contribute to such diseases. Ultimately, nutrigenomics will allow effective dietary-intervention strategies to recover normal homeostasis and to prevent diet-related diseases.
Original languageEnglish
Pages (from-to)315-22
Number of pages8
JournalNature Reviews Genetics
Volume4
Issue number4
DOIs
Publication statusPublished - Apr 2003

Keywords

  • Animals
  • Diet
  • Gene Expression Profiling
  • Genomics
  • Humans
  • Inflammation
  • Mice
  • Mice, Knockout
  • Nutritional Physiological Phenomena
  • Oxidative Stress
  • Research Design

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