Oligodendrocyte–neuron myelinating coculture

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)


The preparation of oligodendrocytes and neurons independently in vitro has provided substantial insight into the biology of the process of myelin sheath formation. This chapter describes a myelination system of dorsal root ganglion neurons by independent isolation of oligodendrocyte progenitor cells from either rat or mouse cortex. This in vitro assay can be used to examine the molecular determinants of myelin sheath formation.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc
Number of pages18
Publication statusPublished - 1 Mar 2019

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745


  • Coculture
  • Dorsal root ganglion
  • In vitro
  • Myelin sheath
  • Myelination
  • Oligodendrocyte
  • Oligodendrocyte progenitor

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