Oligomeric Acylphloroglucinols from Myrtle (Myrtus communis)

Giovanni Appendino, Federica Bianchi, Alberto Minassi, Olov Sterner, Mauro Ballero, Simon Gibbons

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Abstract

The dimeric nonprenylated acylphloroglucinol semimyrtucommulone (6) was obtained from the leaves of myrtle (Myrtus communis) as a 2:1 mixture of two rotamers. The known trimeric phloroglucinol myrtucommulone A (1) was also isolated and characterized spectroscopically as a silylated cyclized derivative (5). Myrtucommulone A showed significant antibacterial activity against multidrug-resistant (MDR) clinically relevant bacteria, while semimyrtucommulone was less active.
Original languageEnglish
Pages (from-to)334-338
Number of pages5
JournalJournal of Natural Products
Volume65
Issue number3
DOIs
Publication statusPublished - 1 Mar 2002

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