OMERACT definition and reliability assessment of chronic ultrasound lesions of the axillary artery in giant cell arteritis

Valentin Sebastian Schäfer; Stavros Chrysidis; Wolfgang A. Schmidt; Christina Duftner; Annamaria Iagnocco; George A. Bruyn; Greta Carrara; Eugenio De Miguel; Andreas P. Diamantopoulos; Berit Dalsgaard Nielsen; Ulrich Fredberg; Wolfgang Hartung; Petra Hanova; Ib Tønder Hansen; Alojzija Hocevar; Aaron Juche; Tanaz A. Kermani; Tove Lorenzen; Pierluigi Macchioni; Marcin Milchert; Uffe Møller Døhn; Chetan Mukhtyar; Sara Monti; Cristina Ponte; Luca Seitz; Carlo A. Scirè; Lene Terslev; Bhaskar Dasgupta; Helen I. Keen; Carlos Pineda; Christian Dejaco

doi:10.1016/j.semarthrit.2021.04.014

OMERACT definition and reliability assessment of chronic ultrasound lesions of the axillary artery in giant cell arteritis

Valentin Sebastian Schäfer, Stavros Chrysidis, Wolfgang A. Schmidt, Christina Duftner, Annamaria Iagnocco, George A. Bruyn, Greta Carrara, Eugenio De Miguel, Andreas P. Diamantopoulos, Berit Dalsgaard Nielsen, Ulrich Fredberg, Wolfgang Hartung, Petra Hanova, Ib Tønder Hansen, Alojzija Hocevar, Aaron Juche, Tanaz A. Kermani, Tove Lorenzen, Pierluigi Macchioni, Marcin MilchertUffe Møller Døhn, Chetan Mukhtyar, Sara Monti, Cristina Ponte, Luca Seitz, Carlo A. Scirè, Lene Terslev, Bhaskar Dasgupta, Helen I. Keen, Carlos Pineda, Christian Dejaco

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Objectives: To define chronic ultrasound lesions of the axillary artery (AA) in long-standing giant cell arteritis (GCA) and to evaluate the reliability of the new ultrasound definition in a web-based exercise. Methods: A structured Delphi, involving an expert panel of the Large Vessel Vasculitis subgroup of the Outcome Measures in Rheumatology (OMERACT) Ultrasound Working Group was carried out. The reliability of the new definition was tested in a 2-round web-based exercise involving 23 experts and using 50 still images each from AA of long-standing and acute GCA patients, as well as 50 images from healthy individuals. Results: The final OMERACT ultrasound definition of chronic changes was based on measurement and appearance of the intima-media complex. The overall reliability of the new definition for chronic ultrasound changes in longstanding GCA of the AA was good to excellent with Light's kappa values of 0.79-0.80 for inter-reader reliability and mean Light's-kappa of 0.88 for intra-reader reliability. The mean inter-rater and intra-rater agreements were 86-87% and 92%, respectively. Good reliabilities were observed comparing the vessels with longstanding versus acute GCA with a mean agreement and kappa values of 81% and 0.63, respectively. Conclusion: The new OMERACT ultrasound definition for chronic vasculitis of the AA in GCA revealed a good to excellent inter- and intra-reader reliability in a web-based exercise of experts.

Original language	English
Pages (from-to)	951-956
Number of pages	6
Journal	Seminars in Arthritis and Rheumatism
Volume	51
Issue number	4
Early online date	18 May 2021
DOIs	https://doi.org/10.1016/j.semarthrit.2021.04.014
Publication status	Published - Aug 2021
Externally published	Yes

Keywords

Axillary artery
Chronic
Definition
Giant cell arteritis
OMERACT
Ultrasound

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10.1016/j.semarthrit.2021.04.014

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Schäfer, V. S., Chrysidis, S., Schmidt, W. A., Duftner, C., Iagnocco, A., Bruyn, G. A., Carrara, G., De Miguel, E., Diamantopoulos, A. P., Nielsen, B. D., Fredberg, U., Hartung, W., Hanova, P., Hansen, I. T., Hocevar, A., Juche, A., Kermani, T. A., Lorenzen, T., Macchioni, P., ... Dejaco, C. (2021). OMERACT definition and reliability assessment of chronic ultrasound lesions of the axillary artery in giant cell arteritis. Seminars in Arthritis and Rheumatism, 51(4), 951-956. https://doi.org/10.1016/j.semarthrit.2021.04.014

Schäfer, Valentin Sebastian ; Chrysidis, Stavros ; Schmidt, Wolfgang A. ; Duftner, Christina ; Iagnocco, Annamaria ; Bruyn, George A. ; Carrara, Greta ; De Miguel, Eugenio ; Diamantopoulos, Andreas P. ; Nielsen, Berit Dalsgaard ; Fredberg, Ulrich ; Hartung, Wolfgang ; Hanova, Petra ; Hansen, Ib Tønder ; Hocevar, Alojzija ; Juche, Aaron ; Kermani, Tanaz A. ; Lorenzen, Tove ; Macchioni, Pierluigi ; Milchert, Marcin ; Døhn, Uffe Møller ; Mukhtyar, Chetan ; Monti, Sara ; Ponte, Cristina ; Seitz, Luca ; Scirè, Carlo A. ; Terslev, Lene ; Dasgupta, Bhaskar ; Keen, Helen I. ; Pineda, Carlos ; Dejaco, Christian. / OMERACT definition and reliability assessment of chronic ultrasound lesions of the axillary artery in giant cell arteritis. In: Seminars in Arthritis and Rheumatism. 2021 ; Vol. 51, No. 4. pp. 951-956.

@article{144ea31786e04b00b7636805535cce7b,

title = "OMERACT definition and reliability assessment of chronic ultrasound lesions of the axillary artery in giant cell arteritis",

abstract = "Objectives: To define chronic ultrasound lesions of the axillary artery (AA) in long-standing giant cell arteritis (GCA) and to evaluate the reliability of the new ultrasound definition in a web-based exercise. Methods: A structured Delphi, involving an expert panel of the Large Vessel Vasculitis subgroup of the Outcome Measures in Rheumatology (OMERACT) Ultrasound Working Group was carried out. The reliability of the new definition was tested in a 2-round web-based exercise involving 23 experts and using 50 still images each from AA of long-standing and acute GCA patients, as well as 50 images from healthy individuals. Results: The final OMERACT ultrasound definition of chronic changes was based on measurement and appearance of the intima-media complex. The overall reliability of the new definition for chronic ultrasound changes in longstanding GCA of the AA was good to excellent with Light's kappa values of 0.79-0.80 for inter-reader reliability and mean Light's-kappa of 0.88 for intra-reader reliability. The mean inter-rater and intra-rater agreements were 86-87% and 92%, respectively. Good reliabilities were observed comparing the vessels with longstanding versus acute GCA with a mean agreement and kappa values of 81% and 0.63, respectively. Conclusion: The new OMERACT ultrasound definition for chronic vasculitis of the AA in GCA revealed a good to excellent inter- and intra-reader reliability in a web-based exercise of experts.",

keywords = "Axillary artery, Chronic, Definition, Giant cell arteritis, OMERACT, Ultrasound",

author = "Sch{\"a}fer, {Valentin Sebastian} and Stavros Chrysidis and Schmidt, {Wolfgang A.} and Christina Duftner and Annamaria Iagnocco and Bruyn, {George A.} and Greta Carrara and {De Miguel}, Eugenio and Diamantopoulos, {Andreas P.} and Nielsen, {Berit Dalsgaard} and Ulrich Fredberg and Wolfgang Hartung and Petra Hanova and Hansen, {Ib T{\o}nder} and Alojzija Hocevar and Aaron Juche and Kermani, {Tanaz A.} and Tove Lorenzen and Pierluigi Macchioni and Marcin Milchert and D{\o}hn, {Uffe M{\o}ller} and Chetan Mukhtyar and Sara Monti and Cristina Ponte and Luca Seitz and Scir{\`e}, {Carlo A.} and Lene Terslev and Bhaskar Dasgupta and Keen, {Helen I.} and Carlos Pineda and Christian Dejaco",

note = "Funding Information: None. No specific funding was received from any bodies in the public, commercial or not-for-profit sectors to carry out the work described in this article. Publisher Copyright: {\textcopyright} 2021 Elsevier Inc.",

year = "2021",

month = aug,

doi = "10.1016/j.semarthrit.2021.04.014",

language = "English",

volume = "51",

pages = "951--956",

journal = "Seminars in Arthritis and Rheumatism",

issn = "0049-0172",

publisher = "W.B. Saunders Ltd",

number = "4",

}

Schäfer, VS, Chrysidis, S, Schmidt, WA, Duftner, C, Iagnocco, A, Bruyn, GA, Carrara, G, De Miguel, E, Diamantopoulos, AP, Nielsen, BD, Fredberg, U, Hartung, W, Hanova, P, Hansen, IT, Hocevar, A, Juche, A, Kermani, TA, Lorenzen, T, Macchioni, P, Milchert, M, Døhn, UM, Mukhtyar, C, Monti, S, Ponte, C, Seitz, L, Scirè, CA, Terslev, L, Dasgupta, B, Keen, HI, Pineda, C & Dejaco, C 2021, 'OMERACT definition and reliability assessment of chronic ultrasound lesions of the axillary artery in giant cell arteritis', Seminars in Arthritis and Rheumatism, vol. 51, no. 4, pp. 951-956. https://doi.org/10.1016/j.semarthrit.2021.04.014

OMERACT definition and reliability assessment of chronic ultrasound lesions of the axillary artery in giant cell arteritis. / Schäfer, Valentin Sebastian; Chrysidis, Stavros; Schmidt, Wolfgang A.; Duftner, Christina; Iagnocco, Annamaria; Bruyn, George A.; Carrara, Greta; De Miguel, Eugenio; Diamantopoulos, Andreas P.; Nielsen, Berit Dalsgaard; Fredberg, Ulrich; Hartung, Wolfgang; Hanova, Petra; Hansen, Ib Tønder; Hocevar, Alojzija; Juche, Aaron; Kermani, Tanaz A.; Lorenzen, Tove; Macchioni, Pierluigi; Milchert, Marcin; Døhn, Uffe Møller; Mukhtyar, Chetan; Monti, Sara; Ponte, Cristina; Seitz, Luca; Scirè, Carlo A.; Terslev, Lene; Dasgupta, Bhaskar; Keen, Helen I.; Pineda, Carlos; Dejaco, Christian.

In: Seminars in Arthritis and Rheumatism, Vol. 51, No. 4, 08.2021, p. 951-956.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - OMERACT definition and reliability assessment of chronic ultrasound lesions of the axillary artery in giant cell arteritis

AU - Schäfer, Valentin Sebastian

AU - Chrysidis, Stavros

AU - Schmidt, Wolfgang A.

AU - Duftner, Christina

AU - Iagnocco, Annamaria

AU - Bruyn, George A.

AU - Carrara, Greta

AU - De Miguel, Eugenio

AU - Diamantopoulos, Andreas P.

AU - Nielsen, Berit Dalsgaard

AU - Fredberg, Ulrich

AU - Hartung, Wolfgang

AU - Hanova, Petra

AU - Hansen, Ib Tønder

AU - Hocevar, Alojzija

AU - Juche, Aaron

AU - Kermani, Tanaz A.

AU - Lorenzen, Tove

AU - Macchioni, Pierluigi

AU - Milchert, Marcin

AU - Døhn, Uffe Møller

AU - Mukhtyar, Chetan

AU - Monti, Sara

AU - Ponte, Cristina

AU - Seitz, Luca

AU - Scirè, Carlo A.

AU - Terslev, Lene

AU - Dasgupta, Bhaskar

AU - Keen, Helen I.

AU - Pineda, Carlos

AU - Dejaco, Christian

N1 - Funding Information: None. No specific funding was received from any bodies in the public, commercial or not-for-profit sectors to carry out the work described in this article. Publisher Copyright: © 2021 Elsevier Inc.

PY - 2021/8

Y1 - 2021/8

N2 - Objectives: To define chronic ultrasound lesions of the axillary artery (AA) in long-standing giant cell arteritis (GCA) and to evaluate the reliability of the new ultrasound definition in a web-based exercise. Methods: A structured Delphi, involving an expert panel of the Large Vessel Vasculitis subgroup of the Outcome Measures in Rheumatology (OMERACT) Ultrasound Working Group was carried out. The reliability of the new definition was tested in a 2-round web-based exercise involving 23 experts and using 50 still images each from AA of long-standing and acute GCA patients, as well as 50 images from healthy individuals. Results: The final OMERACT ultrasound definition of chronic changes was based on measurement and appearance of the intima-media complex. The overall reliability of the new definition for chronic ultrasound changes in longstanding GCA of the AA was good to excellent with Light's kappa values of 0.79-0.80 for inter-reader reliability and mean Light's-kappa of 0.88 for intra-reader reliability. The mean inter-rater and intra-rater agreements were 86-87% and 92%, respectively. Good reliabilities were observed comparing the vessels with longstanding versus acute GCA with a mean agreement and kappa values of 81% and 0.63, respectively. Conclusion: The new OMERACT ultrasound definition for chronic vasculitis of the AA in GCA revealed a good to excellent inter- and intra-reader reliability in a web-based exercise of experts.

AB - Objectives: To define chronic ultrasound lesions of the axillary artery (AA) in long-standing giant cell arteritis (GCA) and to evaluate the reliability of the new ultrasound definition in a web-based exercise. Methods: A structured Delphi, involving an expert panel of the Large Vessel Vasculitis subgroup of the Outcome Measures in Rheumatology (OMERACT) Ultrasound Working Group was carried out. The reliability of the new definition was tested in a 2-round web-based exercise involving 23 experts and using 50 still images each from AA of long-standing and acute GCA patients, as well as 50 images from healthy individuals. Results: The final OMERACT ultrasound definition of chronic changes was based on measurement and appearance of the intima-media complex. The overall reliability of the new definition for chronic ultrasound changes in longstanding GCA of the AA was good to excellent with Light's kappa values of 0.79-0.80 for inter-reader reliability and mean Light's-kappa of 0.88 for intra-reader reliability. The mean inter-rater and intra-rater agreements were 86-87% and 92%, respectively. Good reliabilities were observed comparing the vessels with longstanding versus acute GCA with a mean agreement and kappa values of 81% and 0.63, respectively. Conclusion: The new OMERACT ultrasound definition for chronic vasculitis of the AA in GCA revealed a good to excellent inter- and intra-reader reliability in a web-based exercise of experts.

KW - Axillary artery

KW - Chronic

KW - Definition

KW - Giant cell arteritis

KW - OMERACT

KW - Ultrasound

UR - http://www.scopus.com/inward/record.url?scp=85107983562&partnerID=8YFLogxK

U2 - 10.1016/j.semarthrit.2021.04.014

DO - 10.1016/j.semarthrit.2021.04.014

M3 - Article

C2 - 34140184

AN - SCOPUS:85107983562

VL - 51

SP - 951

EP - 956

JO - Seminars in Arthritis and Rheumatism

JF - Seminars in Arthritis and Rheumatism

SN - 0049-0172

IS - 4

ER -

OMERACT definition and reliability assessment of chronic ultrasound lesions of the axillary artery in giant cell arteritis

Abstract

Keywords

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