TY - JOUR
T1 - OMERACT definition and reliability assessment of chronic ultrasound lesions of the axillary artery in giant cell arteritis
AU - Schäfer, Valentin Sebastian
AU - Chrysidis, Stavros
AU - Schmidt, Wolfgang A.
AU - Duftner, Christina
AU - Iagnocco, Annamaria
AU - Bruyn, George A.
AU - Carrara, Greta
AU - De Miguel, Eugenio
AU - Diamantopoulos, Andreas P.
AU - Nielsen, Berit Dalsgaard
AU - Fredberg, Ulrich
AU - Hartung, Wolfgang
AU - Hanova, Petra
AU - Hansen, Ib Tønder
AU - Hocevar, Alojzija
AU - Juche, Aaron
AU - Kermani, Tanaz A.
AU - Lorenzen, Tove
AU - Macchioni, Pierluigi
AU - Milchert, Marcin
AU - Døhn, Uffe Møller
AU - Mukhtyar, Chetan
AU - Monti, Sara
AU - Ponte, Cristina
AU - Seitz, Luca
AU - Scirè, Carlo A.
AU - Terslev, Lene
AU - Dasgupta, Bhaskar
AU - Keen, Helen I.
AU - Pineda, Carlos
AU - Dejaco, Christian
N1 - Funding Information: None. No specific funding was received from any bodies in the public, commercial or not-for-profit sectors to carry out the work described in this article.
PY - 2021/8
Y1 - 2021/8
N2 - Objectives: To define chronic ultrasound lesions of the axillary artery (AA) in long-standing giant cell arteritis (GCA) and to evaluate the reliability of the new ultrasound definition in a web-based exercise. Methods: A structured Delphi, involving an expert panel of the Large Vessel Vasculitis subgroup of the Outcome Measures in Rheumatology (OMERACT) Ultrasound Working Group was carried out. The reliability of the new definition was tested in a 2-round web-based exercise involving 23 experts and using 50 still images each from AA of long-standing and acute GCA patients, as well as 50 images from healthy individuals. Results: The final OMERACT ultrasound definition of chronic changes was based on measurement and appearance of the intima-media complex. The overall reliability of the new definition for chronic ultrasound changes in longstanding GCA of the AA was good to excellent with Light's kappa values of 0.79-0.80 for inter-reader reliability and mean Light's-kappa of 0.88 for intra-reader reliability. The mean inter-rater and intra-rater agreements were 86-87% and 92%, respectively. Good reliabilities were observed comparing the vessels with longstanding versus acute GCA with a mean agreement and kappa values of 81% and 0.63, respectively. Conclusion: The new OMERACT ultrasound definition for chronic vasculitis of the AA in GCA revealed a good to excellent inter- and intra-reader reliability in a web-based exercise of experts.
AB - Objectives: To define chronic ultrasound lesions of the axillary artery (AA) in long-standing giant cell arteritis (GCA) and to evaluate the reliability of the new ultrasound definition in a web-based exercise. Methods: A structured Delphi, involving an expert panel of the Large Vessel Vasculitis subgroup of the Outcome Measures in Rheumatology (OMERACT) Ultrasound Working Group was carried out. The reliability of the new definition was tested in a 2-round web-based exercise involving 23 experts and using 50 still images each from AA of long-standing and acute GCA patients, as well as 50 images from healthy individuals. Results: The final OMERACT ultrasound definition of chronic changes was based on measurement and appearance of the intima-media complex. The overall reliability of the new definition for chronic ultrasound changes in longstanding GCA of the AA was good to excellent with Light's kappa values of 0.79-0.80 for inter-reader reliability and mean Light's-kappa of 0.88 for intra-reader reliability. The mean inter-rater and intra-rater agreements were 86-87% and 92%, respectively. Good reliabilities were observed comparing the vessels with longstanding versus acute GCA with a mean agreement and kappa values of 81% and 0.63, respectively. Conclusion: The new OMERACT ultrasound definition for chronic vasculitis of the AA in GCA revealed a good to excellent inter- and intra-reader reliability in a web-based exercise of experts.
KW - Axillary artery
KW - Chronic
KW - Definition
KW - Giant cell arteritis
KW - OMERACT
KW - Ultrasound
UR - http://www.scopus.com/inward/record.url?scp=85107983562&partnerID=8YFLogxK
U2 - 10.1016/j.semarthrit.2021.04.014
DO - 10.1016/j.semarthrit.2021.04.014
M3 - Article
C2 - 34140184
AN - SCOPUS:85107983562
SN - 0049-0172
VL - 51
SP - 951
EP - 956
JO - Seminars in Arthritis and Rheumatism
JF - Seminars in Arthritis and Rheumatism
IS - 4
ER -