Transcription factors and their binding sites have become a focal point of bioinformaties research since it became clear that regulatory networks are a centerpiece of genetic information processing. Understanding how genetic information controls and organizes complex biological processes, such as metabolic dynamics, development and morphogenesis, is a major challenge which is addressed by current bioinformatic modelling. The process of realizing phenotypic properties encoded in DNA sequences necessarily involves sequence specific contacts between DNA subsequences and molecules with a biological activity.
|Title of host publication||Function and Regulation of Cellular Systems: Experiments and Models|
|Editors||Andreas Deutsch, Jonathan Howard, Martin Falcke, Walter Zimmermann|
|Number of pages||6|
|Publication status||Published - Feb 2004|
|Name||Mathematics and Biosciences in Interaction|