Abstract
A novel method for the preparation of 9-aminomethylanthracene 1 has been developed by the use of ammonium salts in the reductive amination of the 9-formyl anthracene derivative 2, a reaction which has been examined with a variety of reducing agents, ammonium ion sources and solvents. The optimized reaction conditions allowed the isolation of fluorophore 1 in good yields.
| Original language | English |
|---|---|
| Pages (from-to) | 1733-1737 |
| Number of pages | 6 |
| Journal | Synlett |
| Volume | 27 |
| Issue number | 11 |
| Early online date | 4 Apr 2016 |
| DOIs | |
| Publication status | Published - Jul 2016 |
Keywords
- fluorophore
- one-pot
- reductive amination
- ammonium chloride
- 9-aminomethylathracene