One-pot synthesis of 9-aminomethylanthracene

Paulina Glowacka, George Stephenson

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A novel method for the preparation of 9-aminomethylanthracene 1 has been developed by the use of ammonium salts in the reductive amination of the 9-formyl anthracene derivative 2, a reaction which has been examined with a variety of reducing agents, ammonium ion sources and solvents. The optimized reaction conditions allowed the isolation of fluorophore 1 in good yields.
Original languageEnglish
Pages (from-to)1733-1737
Number of pages6
Issue number11
Early online date4 Apr 2016
Publication statusPublished - Jul 2016


  • fluorophore
  • one-pot
  • reductive amination
  • ammonium chloride
  • 9-aminomethylathracene

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