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One-pot synthesis of 9-aminomethylanthracene

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    Abstract

    A novel method for the preparation of 9-aminomethylanthracene 1 has been developed by the use of ammonium salts in the reductive amination of the 9-formyl anthracene derivative 2, a reaction which has been examined with a variety of reducing agents, ammonium ion sources and solvents. The optimized reaction conditions allowed the isolation of fluorophore 1 in good yields.
    Original languageEnglish
    Pages (from-to)1733-1737
    Number of pages6
    JournalSynlett
    Volume27
    Issue number11
    Early online date4 Apr 2016
    DOIs
    Publication statusPublished - Jul 2016

    Keywords

    • fluorophore
    • one-pot
    • reductive amination
    • ammonium chloride
    • 9-aminomethylathracene

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