Opacification induced by calcium overload in sheep lens culture

H. Y. Y. Lee; J. D. Morton; L. J. G. Robertson; J. Sanderson

Opacification induced by calcium overload in sheep lens culture

H. Y. Y. Lee, J. D. Morton, L. J. G. Robertson, J. Sanderson

Research output: Contribution to journal › Article

Abstract

The sheep lens culture system has been developed as an alternative, controlled model of cataract formation allowing the measurement of early changes in cataractogenesis and the ability to test the efficacy of calpain inhibitors in preventing cataracts. The purpose of this experiment was to confirm a causal link between calpain activation and lens opacification.

Original language	English
Pages (from-to)	2652
Number of pages	1
Journal	Investigative Ophthalmology and Visual Science
Volume	45
Publication status	Published - 2004

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https://iovs.arvojournals.org/article.aspx?articleid=2408193

Cite this

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title = "Opacification induced by calcium overload in sheep lens culture",

abstract = "The sheep lens culture system has been developed as an alternative, controlled model of cataract formation allowing the measurement of early changes in cataractogenesis and the ability to test the efficacy of calpain inhibitors in preventing cataracts. The purpose of this experiment was to confirm a causal link between calpain activation and lens opacification.",

author = "Lee, {H. Y. Y.} and Morton, {J. D.} and Robertson, {L. J. G.} and J. Sanderson",

year = "2004",

language = "English",

volume = "45",

pages = "2652",

journal = "Investigative Ophthalmology and Visual Science",

issn = "0146-0404",

publisher = "Association for Research in Vision and Ophthalmology Inc.",

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T1 - Opacification induced by calcium overload in sheep lens culture

AU - Lee, H. Y. Y.

AU - Morton, J. D.

AU - Robertson, L. J. G.

AU - Sanderson, J.

PY - 2004

Y1 - 2004

N2 - The sheep lens culture system has been developed as an alternative, controlled model of cataract formation allowing the measurement of early changes in cataractogenesis and the ability to test the efficacy of calpain inhibitors in preventing cataracts. The purpose of this experiment was to confirm a causal link between calpain activation and lens opacification.

AB - The sheep lens culture system has been developed as an alternative, controlled model of cataract formation allowing the measurement of early changes in cataractogenesis and the ability to test the efficacy of calpain inhibitors in preventing cataracts. The purpose of this experiment was to confirm a causal link between calpain activation and lens opacification.

M3 - Article

VL - 45

SP - 2652

JO - Investigative Ophthalmology and Visual Science

JF - Investigative Ophthalmology and Visual Science

SN - 0146-0404

ER -