Oral ferrous sulfate supplements increase the free radical-generating capacity of feces from healthy volunteers

E K Lund, S G Wharf, S J Fairweather-Tait, I T Johnson

Research output: Contribution to journalArticlepeer-review

193 Citations (Scopus)


Most dietary iron remains unabsorbed and hence may be available to participate in Fenton-driven free radical generation in conjunction with the colonic microflora, leading to the production of carcinogens or direct damage to colonocytes.
Original languageEnglish
Pages (from-to)250-5
Number of pages6
JournalAmerican Journal of Clinical Nutrition
Issue number2
Publication statusPublished - Feb 1999


  • Administration, Oral
  • Adult
  • Colonic Neoplasms
  • Diet
  • Dietary Supplements
  • Feces
  • Female
  • Ferrous Compounds
  • Free Radicals
  • Humans
  • Iron
  • Linear Models
  • Male
  • Middle Aged
  • Reactive Oxygen Species
  • Reference Values
  • Risk Factors

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