Oral ferrous sulfate supplements increase the free radical-generating capacity of feces from healthy volunteers

E K Lund; S G Wharf; S J Fairweather-Tait; I T Johnson

Oral ferrous sulfate supplements increase the free radical-generating capacity of feces from healthy volunteers

E K Lund
, S G Wharf
, S J Fairweather-Tait
, I T Johnson

Research output: Contribution to journal › Article › peer-review

204 Citations (Scopus)

Abstract

Most dietary iron remains unabsorbed and hence may be available to participate in Fenton-driven free radical generation in conjunction with the colonic microflora, leading to the production of carcinogens or direct damage to colonocytes.

Original language	English
Pages (from-to)	250-5
Number of pages	6
Journal	American Journal of Clinical Nutrition
Volume	69
Issue number	2
Publication status	Published - Feb 1999

Keywords

Administration, Oral
Adult
Colonic Neoplasms
Diet
Dietary Supplements
Feces
Female
Ferrous Compounds
Free Radicals
Humans
Iron
Linear Models
Male
Middle Aged
Reactive Oxygen Species
Reference Values
Risk Factors

Cite this

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title = "Oral ferrous sulfate supplements increase the free radical-generating capacity of feces from healthy volunteers",

abstract = "Most dietary iron remains unabsorbed and hence may be available to participate in Fenton-driven free radical generation in conjunction with the colonic microflora, leading to the production of carcinogens or direct damage to colonocytes.",

keywords = "Administration, Oral, Adult, Colonic Neoplasms, Diet, Dietary Supplements, Feces, Female, Ferrous Compounds, Free Radicals, Humans, Iron, Linear Models, Male, Middle Aged, Reactive Oxygen Species, Reference Values, Risk Factors",

author = "Lund, \{E K\} and Wharf, \{S G\} and Fairweather-Tait, \{S J\} and Johnson, \{I T\}",

year = "1999",

month = feb,

language = "English",

volume = "69",

pages = "250--5",

journal = "American Journal of Clinical Nutrition",

issn = "0002-9165",

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T1 - Oral ferrous sulfate supplements increase the free radical-generating capacity of feces from healthy volunteers

AU - Lund, E K

AU - Wharf, S G

AU - Fairweather-Tait, S J

AU - Johnson, I T

PY - 1999/2

Y1 - 1999/2

N2 - Most dietary iron remains unabsorbed and hence may be available to participate in Fenton-driven free radical generation in conjunction with the colonic microflora, leading to the production of carcinogens or direct damage to colonocytes.

AB - Most dietary iron remains unabsorbed and hence may be available to participate in Fenton-driven free radical generation in conjunction with the colonic microflora, leading to the production of carcinogens or direct damage to colonocytes.

KW - Administration, Oral

KW - Adult

KW - Colonic Neoplasms

KW - Diet

KW - Dietary Supplements

KW - Feces

KW - Female

KW - Ferrous Compounds

KW - Free Radicals

KW - Humans

KW - Iron

KW - Linear Models

KW - Male

KW - Middle Aged

KW - Reactive Oxygen Species

KW - Reference Values

KW - Risk Factors

M3 - Article

C2 - 9989688

SN - 0002-9165

VL - 69

SP - 250

EP - 255

JO - American Journal of Clinical Nutrition

JF - American Journal of Clinical Nutrition

IS - 2

ER -