Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, Brazil

Libera M Dalla-Costa; Juliana M Coelho; Helena A P H M Souza; Maria E S Castro; Christiane J N Stier; Karin L Bragagnolo; Alvaro Rea-Neto; Sergio R Penteado-Filho; David M Livermore; Neil Woodford

Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, Brazil

Libera M Dalla-Costa, Juliana M Coelho, Helena A P H M Souza, Maria E S Castro, Christiane J N Stier, Karin L Bragagnolo, Alvaro Rea-Neto, Sergio R Penteado-Filho, David M Livermore, Neil Woodford

Research output: Contribution to journal › Article › peer-review

173 Citations (Scopus)

Abstract

Carbapenem-resistant Acinetobacter baumannii isolates were obtained from eight patients in two hospitals in Curitiba, Brazil. The isolates were multiresistant, belonged to a single strain, and produced the OXA-23 carbapenemase. Treatment options were limited, although the isolates were susceptible to polymyxin B in vitro. The strain contributed to the deaths of five patients.

Original language	English
Pages (from-to)	3403-6
Number of pages	4
Journal	Journal of Clinical Microbiology
Volume	41
Issue number	7
Publication status	Published - Jul 2003

Keywords

Acinetobacter Infections
Acinetobacter baumannii
Adult
Aged
Aged, 80 and over
Brazil
Carbapenems
Disease Outbreaks
Drug Resistance, Bacterial
Hospitals, Teaching
Humans
Microbial Sensitivity Tests
Middle Aged
beta-Lactamases

Cite this

Dalla-Costa, Libera M ; Coelho, Juliana M ; Souza, Helena A P H M ; Castro, Maria E S ; Stier, Christiane J N ; Bragagnolo, Karin L ; Rea-Neto, Alvaro ; Penteado-Filho, Sergio R ; Livermore, David M ; Woodford, Neil. / Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, Brazil. In: Journal of Clinical Microbiology. 2003 ; Vol. 41, No. 7. pp. 3403-6.

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title = "Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, Brazil",

abstract = "Carbapenem-resistant Acinetobacter baumannii isolates were obtained from eight patients in two hospitals in Curitiba, Brazil. The isolates were multiresistant, belonged to a single strain, and produced the OXA-23 carbapenemase. Treatment options were limited, although the isolates were susceptible to polymyxin B in vitro. The strain contributed to the deaths of five patients.",

keywords = "Acinetobacter Infections, Acinetobacter baumannii, Adult, Aged, Aged, 80 and over, Brazil, Carbapenems, Disease Outbreaks, Drug Resistance, Bacterial, Hospitals, Teaching, Humans, Microbial Sensitivity Tests, Middle Aged, beta-Lactamases",

author = "Dalla-Costa, {Libera M} and Coelho, {Juliana M} and Souza, {Helena A P H M} and Castro, {Maria E S} and Stier, {Christiane J N} and Bragagnolo, {Karin L} and Alvaro Rea-Neto and Penteado-Filho, {Sergio R} and Livermore, {David M} and Neil Woodford",

year = "2003",

month = jul,

language = "English",

volume = "41",

pages = "3403--6",

journal = "Journal of Clinical Microbiology",

issn = "0095-1137",

publisher = "American Society for Microbiology",

number = "7",

}

Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, Brazil. / Dalla-Costa, Libera M; Coelho, Juliana M; Souza, Helena A P H M; Castro, Maria E S; Stier, Christiane J N; Bragagnolo, Karin L; Rea-Neto, Alvaro; Penteado-Filho, Sergio R; Livermore, David M; Woodford, Neil.

In: Journal of Clinical Microbiology, Vol. 41, No. 7, 07.2003, p. 3403-6.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, Brazil

AU - Dalla-Costa, Libera M

AU - Coelho, Juliana M

AU - Souza, Helena A P H M

AU - Castro, Maria E S

AU - Stier, Christiane J N

AU - Bragagnolo, Karin L

AU - Rea-Neto, Alvaro

AU - Penteado-Filho, Sergio R

AU - Livermore, David M

AU - Woodford, Neil

PY - 2003/7

Y1 - 2003/7

N2 - Carbapenem-resistant Acinetobacter baumannii isolates were obtained from eight patients in two hospitals in Curitiba, Brazil. The isolates were multiresistant, belonged to a single strain, and produced the OXA-23 carbapenemase. Treatment options were limited, although the isolates were susceptible to polymyxin B in vitro. The strain contributed to the deaths of five patients.

AB - Carbapenem-resistant Acinetobacter baumannii isolates were obtained from eight patients in two hospitals in Curitiba, Brazil. The isolates were multiresistant, belonged to a single strain, and produced the OXA-23 carbapenemase. Treatment options were limited, although the isolates were susceptible to polymyxin B in vitro. The strain contributed to the deaths of five patients.

KW - Acinetobacter Infections

KW - Acinetobacter baumannii

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Brazil

KW - Carbapenems

KW - Disease Outbreaks

KW - Drug Resistance, Bacterial

KW - Hospitals, Teaching

KW - Humans

KW - Microbial Sensitivity Tests

KW - Middle Aged

KW - beta-Lactamases

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VL - 41

SP - 3403

EP - 3406

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

SN - 0095-1137

IS - 7

ER -