Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, Brazil

Libera M Dalla-Costa, Juliana M Coelho, Helena A P H M Souza, Maria E S Castro, Christiane J N Stier, Karin L Bragagnolo, Alvaro Rea-Neto, Sergio R Penteado-Filho, David M Livermore, Neil Woodford

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Carbapenem-resistant Acinetobacter baumannii isolates were obtained from eight patients in two hospitals in Curitiba, Brazil. The isolates were multiresistant, belonged to a single strain, and produced the OXA-23 carbapenemase. Treatment options were limited, although the isolates were susceptible to polymyxin B in vitro. The strain contributed to the deaths of five patients.
Original languageEnglish
Pages (from-to)3403-6
Number of pages4
JournalJournal of Clinical Microbiology
Issue number7
Publication statusPublished - Jul 2003


  • Acinetobacter Infections
  • Acinetobacter baumannii
  • Adult
  • Aged
  • Aged, 80 and over
  • Brazil
  • Carbapenems
  • Disease Outbreaks
  • Drug Resistance, Bacterial
  • Hospitals, Teaching
  • Humans
  • Microbial Sensitivity Tests
  • Middle Aged
  • beta-Lactamases

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