Overall similarity and consistency assessment scores are not sufficiently accurate for predicting discrepancy between direct and indirect comparison estimates

Tengbin Xiong, Sheetal Parekh-Bhurke, Yoon K Loke, Asmaa Abdelhamid, Alex J Sutton, Alison J Eastwood, Richard Holland, Yen-Fu Chen, Tanya Walsh, Anne-Marie Glenny, Fujian Song

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12 Citations (Scopus)


Indirect comparison methods have been increasingly used to assess the effectiveness of different interventions comparatively. This study evaluated a Trial Similarity and Evidence Consistency Assessment (TSECA) framework for assessing key assumptions underlying the validity of indirect comparisons.
Original languageEnglish
Pages (from-to)184-191
Number of pages8
JournalJournal of Clinical Epidemiology
Issue number2
Publication statusPublished - Feb 2013


  • Bias (Epidemiology)
  • Evidence-Based Medicine
  • Guideline Adherence
  • Humans
  • Practice Guidelines as Topic
  • Predictive Value of Tests
  • Quality Assurance, Health Care
  • Randomized Controlled Trials as Topic
  • Reproducibility of Results
  • Sensitivity and Specificity

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