Overexpression of RAD51 occurs in aggressive prostatic cancer

Anita Mitra; Charles Jameson; Yolanda Barbachano; Lydia Sanchez; Zsofia Kote-Jarai; Susan Peock; Nayanta Sodha; Elizabeth Bancroft; Anne Fletcher; Colin Cooper; Douglas Easton; Rosalind Eeles; Christopher S Foster; IMPACT Steering Committee and IMPACT and EMBRACE Collaborators

doi:10.1111/j.1365-2559.2009.03448.x

Overexpression of RAD51 occurs in aggressive prostatic cancer

Anita Mitra
, Charles Jameson
, Yolanda Barbachano
, Lydia Sanchez
, Zsofia Kote-Jarai
, Susan Peock
, Nayanta Sodha
, Elizabeth Bancroft
, Anne Fletcher
, Colin Cooper
, Douglas Easton
, Rosalind Eeles
, Christopher S Foster
, IMPACT Steering Committee and IMPACT and EMBRACE Collaborators

Research output: Contribution to journal › Article › peer-review

90 Citations (Scopus)

Abstract

To test the hypothesis that, in a matched series of prostatic cancers, either with or without BRCA1 or BRCA2 mutations, RAD51 protein expression is enhanced in association with BRCA mutation genotypes.

Original language	English
Pages (from-to)	696-704
Number of pages	9
Journal	Histopathology
Volume	55
Issue number	6
DOIs	https://doi.org/10.1111/j.1365-2559.2009.03448.x
Publication status	Published - Dec 2009

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Adult
Aged
Aged, 80 and over
BRCA1 Protein
BRCA2 Protein
Cell Count
Gene Expression Regulation, Neoplastic
Genetic Predisposition to Disease
Germ-Line Mutation
Humans
Immunohistochemistry
Male
Middle Aged
Neoplasm Proteins
Prostatic Neoplasms
Rad51 Recombinase
Severity of Illness Index
Tumor Markers, Biological

Access to Document

10.1111/j.1365-2559.2009.03448.x

Cite this

Mitra, A., Jameson, C., Barbachano, Y., Sanchez, L., Kote-Jarai, Z., Peock, S., Sodha, N., Bancroft, E., Fletcher, A., Cooper, C., Easton, D., Eeles, R., Foster, C. S., & IMPACT Steering Committee and IMPACT and EMBRACE Collaborators (2009). Overexpression of RAD51 occurs in aggressive prostatic cancer. Histopathology, 55(6), 696-704. https://doi.org/10.1111/j.1365-2559.2009.03448.x

@article{1dc52cfe82b8410291ecb529edacf637,

title = "Overexpression of RAD51 occurs in aggressive prostatic cancer",

abstract = "To test the hypothesis that, in a matched series of prostatic cancers, either with or without BRCA1 or BRCA2 mutations, RAD51 protein expression is enhanced in association with BRCA mutation genotypes.",

keywords = "Adult, Aged, Aged, 80 and over, BRCA1 Protein, BRCA2 Protein, Cell Count, Gene Expression Regulation, Neoplastic, Genetic Predisposition to Disease, Germ-Line Mutation, Humans, Immunohistochemistry, Male, Middle Aged, Neoplasm Proteins, Prostatic Neoplasms, Rad51 Recombinase, Severity of Illness Index, Tumor Markers, Biological",

author = "Anita Mitra and Charles Jameson and Yolanda Barbachano and Lydia Sanchez and Zsofia Kote-Jarai and Susan Peock and Nayanta Sodha and Elizabeth Bancroft and Anne Fletcher and Colin Cooper and Douglas Easton and Rosalind Eeles and Foster, \{Christopher S\} and \{IMPACT Steering Committee and IMPACT and EMBRACE Collaborators\}",

year = "2009",

month = dec,

doi = "10.1111/j.1365-2559.2009.03448.x",

language = "English",

volume = "55",

pages = "696--704",

journal = "Histopathology",

issn = "1365-2559",

publisher = "Wiley",

number = "6",

}

Mitra, A, Jameson, C, Barbachano, Y, Sanchez, L, Kote-Jarai, Z, Peock, S, Sodha, N, Bancroft, E, Fletcher, A, Cooper, C, Easton, D, Eeles, R, Foster, CS & IMPACT Steering Committee and IMPACT and EMBRACE Collaborators 2009, 'Overexpression of RAD51 occurs in aggressive prostatic cancer', Histopathology, vol. 55, no. 6, pp. 696-704. https://doi.org/10.1111/j.1365-2559.2009.03448.x

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T1 - Overexpression of RAD51 occurs in aggressive prostatic cancer

AU - Mitra, Anita

AU - Jameson, Charles

AU - Barbachano, Yolanda

AU - Sanchez, Lydia

AU - Kote-Jarai, Zsofia

AU - Peock, Susan

AU - Sodha, Nayanta

AU - Bancroft, Elizabeth

AU - Fletcher, Anne

AU - Cooper, Colin

AU - Easton, Douglas

AU - Eeles, Rosalind

AU - Foster, Christopher S

AU - IMPACT Steering Committee and IMPACT and EMBRACE Collaborators

PY - 2009/12

Y1 - 2009/12

N2 - To test the hypothesis that, in a matched series of prostatic cancers, either with or without BRCA1 or BRCA2 mutations, RAD51 protein expression is enhanced in association with BRCA mutation genotypes.

AB - To test the hypothesis that, in a matched series of prostatic cancers, either with or without BRCA1 or BRCA2 mutations, RAD51 protein expression is enhanced in association with BRCA mutation genotypes.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - BRCA1 Protein

KW - BRCA2 Protein

KW - Cell Count

KW - Gene Expression Regulation, Neoplastic

KW - Genetic Predisposition to Disease

KW - Germ-Line Mutation

KW - Humans

KW - Immunohistochemistry

KW - Male

KW - Middle Aged

KW - Neoplasm Proteins

KW - Prostatic Neoplasms

KW - Rad51 Recombinase

KW - Severity of Illness Index

KW - Tumor Markers, Biological

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DO - 10.1111/j.1365-2559.2009.03448.x

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SN - 1365-2559

VL - 55

SP - 696

EP - 704

JO - Histopathology

JF - Histopathology

IS - 6

ER -