Paraoxonase-1 is not associated with coronary artery calcification in type 2 diabetes: results from the PREDICT study

Bharti Mackness, Judit Marsillach, Robert S Elkeles, Ian F Godsland, Michael D Feher, Michael B Rubens, Marcus D Flather, Steve E Humphries, Jackie Cooper, Mike Mackness

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15 Citations (Scopus)


To determine any association between serum paraoxonase-1 (PON1) activity, protein and coding region genetic polymorphisms and coronary artery calcification (CACS) and to determine factors which modulate serum PON1 in type 2 diabetes (T2DM).
Original languageEnglish
Pages (from-to)101-112
Number of pages12
JournalDisease Markers
Issue number2
Publication statusPublished - 2012


  • Polymorphism, Single Nucleotide
  • Humans
  • Aged
  • Aryldialkylphosphatase
  • Creatinine
  • European Continental Ancestry Group
  • Triglycerides
  • Diabetes Mellitus, Type 2
  • Middle Aged
  • Insulin Resistance
  • Vascular Calcification
  • Coronary Artery Disease
  • Female
  • Male

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