Paraoxonase-1 is not associated with coronary artery calcification in type 2 diabetes: results from the PREDICT study

Bharti Mackness; Judit Marsillach; Robert S Elkeles; Ian F Godsland; Michael D Feher; Michael B Rubens; Marcus D Flather; Steve E Humphries; Jackie Cooper; Mike Mackness

doi:10.3233/DMA-2012-0910

Paraoxonase-1 is not associated with coronary artery calcification in type 2 diabetes: results from the PREDICT study

Bharti Mackness, Judit Marsillach, Robert S Elkeles, Ian F Godsland, Michael D Feher, Michael B Rubens, Marcus D Flather, Steve E Humphries, Jackie Cooper, Mike Mackness

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

To determine any association between serum paraoxonase-1 (PON1) activity, protein and coding region genetic polymorphisms and coronary artery calcification (CACS) and to determine factors which modulate serum PON1 in type 2 diabetes (T2DM).

Original language	English
Pages (from-to)	101-112
Number of pages	12
Journal	Disease Markers
Volume	33
Issue number	2
DOIs	https://doi.org/10.3233/DMA-2012-0910
Publication status	Published - 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Polymorphism, Single Nucleotide
Humans
Aged
Aryldialkylphosphatase
Creatinine
European Continental Ancestry Group
Triglycerides
Diabetes Mellitus, Type 2
Middle Aged
Insulin Resistance
Vascular Calcification
Coronary Artery Disease
Female
Male

Access to Document

10.3233/DMA-2012-0910

Cite this

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title = "Paraoxonase-1 is not associated with coronary artery calcification in type 2 diabetes: results from the PREDICT study",

abstract = "To determine any association between serum paraoxonase-1 (PON1) activity, protein and coding region genetic polymorphisms and coronary artery calcification (CACS) and to determine factors which modulate serum PON1 in type 2 diabetes (T2DM).",

keywords = "Polymorphism, Single Nucleotide, Humans, Aged, Aryldialkylphosphatase, Creatinine, European Continental Ancestry Group, Triglycerides, Diabetes Mellitus, Type 2, Middle Aged, Insulin Resistance, Vascular Calcification, Coronary Artery Disease, Female, Male",

author = "Bharti Mackness and Judit Marsillach and Elkeles, {Robert S} and Godsland, {Ian F} and Feher, {Michael D} and Rubens, {Michael B} and Flather, {Marcus D} and Humphries, {Steve E} and Jackie Cooper and Mike Mackness",

year = "2012",

doi = "10.3233/DMA-2012-0910",

language = "English",

volume = "33",

pages = "101--112",

journal = "Disease Markers",

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publisher = "IOS Press",

number = "2",

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T1 - Paraoxonase-1 is not associated with coronary artery calcification in type 2 diabetes

T2 - results from the PREDICT study

AU - Mackness, Bharti

AU - Marsillach, Judit

AU - Elkeles, Robert S

AU - Godsland, Ian F

AU - Feher, Michael D

AU - Rubens, Michael B

AU - Flather, Marcus D

AU - Humphries, Steve E

AU - Cooper, Jackie

AU - Mackness, Mike

PY - 2012

Y1 - 2012

N2 - To determine any association between serum paraoxonase-1 (PON1) activity, protein and coding region genetic polymorphisms and coronary artery calcification (CACS) and to determine factors which modulate serum PON1 in type 2 diabetes (T2DM).

AB - To determine any association between serum paraoxonase-1 (PON1) activity, protein and coding region genetic polymorphisms and coronary artery calcification (CACS) and to determine factors which modulate serum PON1 in type 2 diabetes (T2DM).

KW - Polymorphism, Single Nucleotide

KW - Humans

KW - Aged

KW - Aryldialkylphosphatase

KW - Creatinine

KW - European Continental Ancestry Group

KW - Triglycerides

KW - Diabetes Mellitus, Type 2

KW - Middle Aged

KW - Insulin Resistance

KW - Vascular Calcification

KW - Coronary Artery Disease

KW - Female

KW - Male

U2 - 10.3233/DMA-2012-0910

DO - 10.3233/DMA-2012-0910

M3 - Article

C2 - 22846213

SN - 1875-8630

VL - 33

SP - 101

EP - 112

JO - Disease Markers

JF - Disease Markers

IS - 2

ER -