Pathogenomics of non-pathogens

Matthew Holden, Lisa Crossman, Ana Cerdeño-Tárraga, Julian Parkhill

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

Analysing the genomes of non-pathogenic microorganisms, in addition to its basic and applied scientific interest, can also shed considerable light on the study of pathogenic microorganisms. Two of the three microorganisms described here are rarely pathogenic, but carry genetic determinants that have previously been identified as being important for the pathogenicity of other microorganisms. This underlines the growing understanding that many so-called 'virulence genes' are probably involved in more general interactions between the microorganism and the host or the environment.

Original languageEnglish
Pages (from-to)91
Number of pages1
JournalNature Reviews Microbiology
Volume2
Issue number2
DOIs
Publication statusPublished - Feb 2004

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