Pegylation of Antimicrobial Peptides Maintains the Active Peptide Conformation, Model Membrane Interactions, and Antimicrobial Activity while Improving Lung Tissue Biocompatibility following Airway Delivery

Christopher J. Morris; Konrad Beck; Marc A. Fox; David Ulaeto; Graeme C. Clark; Mark Gumbleton

doi:10.1128/AAC.06335-11

Pegylation of Antimicrobial Peptides Maintains the Active Peptide Conformation, Model Membrane Interactions, and Antimicrobial Activity while Improving Lung Tissue Biocompatibility following Airway Delivery

Christopher J. Morris, Konrad Beck, Marc A. Fox, David Ulaeto, Graeme C. Clark, Mark Gumbleton

Research output: Contribution to journal › Article

49 Citations (Scopus)

Original language	English
Pages (from-to)	3298-3308
Number of pages	11
Journal	Antimicrobial Agents and Chemotherapy
Volume	56
Issue number	6
DOIs	https://doi.org/10.1128/AAC.06335-11
Publication status	Published - 2012

Access to Document

10.1128/AAC.06335-11

Cite this

Morris, C. J., Beck, K., Fox, M. A., Ulaeto, D., Clark, G. C., & Gumbleton, M. (2012). Pegylation of Antimicrobial Peptides Maintains the Active Peptide Conformation, Model Membrane Interactions, and Antimicrobial Activity while Improving Lung Tissue Biocompatibility following Airway Delivery. Antimicrobial Agents and Chemotherapy, 56(6), 3298-3308. https://doi.org/10.1128/AAC.06335-11

Morris, Christopher J. ; Beck, Konrad ; Fox, Marc A. ; Ulaeto, David ; Clark, Graeme C. ; Gumbleton, Mark. / Pegylation of Antimicrobial Peptides Maintains the Active Peptide Conformation, Model Membrane Interactions, and Antimicrobial Activity while Improving Lung Tissue Biocompatibility following Airway Delivery. In: Antimicrobial Agents and Chemotherapy. 2012 ; Vol. 56, No. 6. pp. 3298-3308.

@article{ddd43807f47b402c97412aaf540d7b5b,

title = "Pegylation of Antimicrobial Peptides Maintains the Active Peptide Conformation, Model Membrane Interactions, and Antimicrobial Activity while Improving Lung Tissue Biocompatibility following Airway Delivery",

author = "Morris, {Christopher J.} and Konrad Beck and Fox, {Marc A.} and David Ulaeto and Clark, {Graeme C.} and Mark Gumbleton",

year = "2012",

doi = "10.1128/AAC.06335-11",

language = "English",

volume = "56",

pages = "3298--3308",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "6",

}

Morris, CJ, Beck, K, Fox, MA, Ulaeto, D, Clark, GC & Gumbleton, M 2012, 'Pegylation of Antimicrobial Peptides Maintains the Active Peptide Conformation, Model Membrane Interactions, and Antimicrobial Activity while Improving Lung Tissue Biocompatibility following Airway Delivery', Antimicrobial Agents and Chemotherapy, vol. 56, no. 6, pp. 3298-3308. https://doi.org/10.1128/AAC.06335-11

Pegylation of Antimicrobial Peptides Maintains the Active Peptide Conformation, Model Membrane Interactions, and Antimicrobial Activity while Improving Lung Tissue Biocompatibility following Airway Delivery. / Morris, Christopher J.; Beck, Konrad; Fox, Marc A.; Ulaeto, David; Clark, Graeme C.; Gumbleton, Mark.

In: Antimicrobial Agents and Chemotherapy, Vol. 56, No. 6, 2012, p. 3298-3308.

Research output: Contribution to journal › Article

TY - JOUR

T1 - Pegylation of Antimicrobial Peptides Maintains the Active Peptide Conformation, Model Membrane Interactions, and Antimicrobial Activity while Improving Lung Tissue Biocompatibility following Airway Delivery

AU - Morris, Christopher J.

AU - Beck, Konrad

AU - Fox, Marc A.

AU - Ulaeto, David

AU - Clark, Graeme C.

AU - Gumbleton, Mark

PY - 2012

Y1 - 2012

U2 - 10.1128/AAC.06335-11

DO - 10.1128/AAC.06335-11

M3 - Article

VL - 56

SP - 3298

EP - 3308

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

SN - 0066-4804

IS - 6

ER -