Perianal fistulae in Crohn's Disease: current and future approaches to treatment

Hussila Keshaw, Keen S Foong, Alastair Forbes, Richard M Day

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18 Citations (Scopus)


: affecting sphincter integrity and continence. Traditional surgical and medical approaches are not without their limitations and may result in either comorbidity, such as fecal incontinence, or incomplete healing of the fistulae. Over the last 2 decades these limitations have led to a paradigm shift toward the use of biomaterials, and more recently cell-based therapies, which have met with variable degrees of success. This review discusses the traditional and current methods of treatment, as well as emerging and possible alternative approaches that may improve fistula healing.
Original languageEnglish
Pages (from-to)870-80
Number of pages11
JournalInflammatory Bowel Diseases
Issue number5
Publication statusPublished - May 2010


  • Anti-Bacterial Agents
  • Crohn Disease
  • Humans
  • Immunosuppressive Agents
  • Rectal Fistula

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