Peroxisome proliferator activated receptor ligands for the treatment of insulin resistance

David Patsouris; Michael Müller; Sander Kersten

Peroxisome proliferator activated receptor ligands for the treatment of insulin resistance

David Patsouris, Michael Müller, Sander Kersten

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

Peroxisome proliferator activated receptors (PPARs) are a group of ligand-activated transcription factors that play critical roles in the regulation of energy metabolism. Synthetic agonists for these receptors are used in the treatment of type 2 diabetes mellitus and dyslipidemia. Current data linking PPAR and/or PPAR ligands with the treatment of insulin resistance will be critically reviewed, with the focus on important advances over the past year.

Original language	English
Pages (from-to)	1045-1050
Number of pages	6
Journal	Current Opinion in Investigational Drugs
Volume	5
Issue number	10
Publication status	Published - Oct 2004

Keywords

Animals
Diabetes Mellitus, Type 2
Humans
Hypoglycemic Agents
Insulin Resistance
Ligands
Peroxisome Proliferator-Activated Receptors

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

https://pubmed.ncbi.nlm.nih.gov/15535425/

Cite this

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abstract = "Peroxisome proliferator activated receptors (PPARs) are a group of ligand-activated transcription factors that play critical roles in the regulation of energy metabolism. Synthetic agonists for these receptors are used in the treatment of type 2 diabetes mellitus and dyslipidemia. Current data linking PPAR and/or PPAR ligands with the treatment of insulin resistance will be critically reviewed, with the focus on important advances over the past year.",

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AU - Kersten, Sander

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AB - Peroxisome proliferator activated receptors (PPARs) are a group of ligand-activated transcription factors that play critical roles in the regulation of energy metabolism. Synthetic agonists for these receptors are used in the treatment of type 2 diabetes mellitus and dyslipidemia. Current data linking PPAR and/or PPAR ligands with the treatment of insulin resistance will be critically reviewed, with the focus on important advances over the past year.

KW - Animals

KW - Diabetes Mellitus, Type 2

KW - Humans

KW - Hypoglycemic Agents

KW - Insulin Resistance

KW - Ligands

KW - Peroxisome Proliferator-Activated Receptors

M3 - Article

C2 - 15535425

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EP - 1050

JO - Current Opinion in Investigational Drugs

JF - Current Opinion in Investigational Drugs

SN - 1472-4472

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