Peroxisome proliferator activated receptors (PPARs) are a group of ligand-activated transcription factors that play critical roles in the regulation of energy metabolism. Synthetic agonists for these receptors are used in the treatment of type 2 diabetes mellitus and dyslipidemia. Current data linking PPAR and/or PPAR ligands with the treatment of insulin resistance will be critically reviewed, with the focus on important advances over the past year.
|Number of pages||6|
|Journal||Current Opinion in Investigational Drugs|
|Publication status||Published - Oct 2004|
- Diabetes Mellitus, Type 2
- Hypoglycemic Agents
- Insulin Resistance
- Peroxisome Proliferator-Activated Receptors