Peroxisome proliferator activated receptor ligands for the treatment of insulin resistance

David Patsouris, Michael Müller, Sander Kersten

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Peroxisome proliferator activated receptors (PPARs) are a group of ligand-activated transcription factors that play critical roles in the regulation of energy metabolism. Synthetic agonists for these receptors are used in the treatment of type 2 diabetes mellitus and dyslipidemia. Current data linking PPAR and/or PPAR ligands with the treatment of insulin resistance will be critically reviewed, with the focus on important advances over the past year.
Original languageEnglish
Pages (from-to)1045-50
Number of pages6
JournalCurrent Opinion in Investigational Drugs
Volume5
Issue number10
Publication statusPublished - Oct 2004

Keywords

  • Animals
  • Diabetes Mellitus, Type 2
  • Humans
  • Hypoglycemic Agents
  • Insulin Resistance
  • Ligands
  • Peroxisome Proliferator-Activated Receptors

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