Persistence of Klebsiella pneumoniae clones with OXA-48 or NDM carbapenemases causing bacteraemias in a Riyadh hospital

Mohamed H. Al-Agamy; Atef M. Shibl; Noura A. Elkhizzi; Daniele Meunier; Jane F. Turton; David M. Livermore

doi:10.1016/j.diagmicrobio.2013.02.006

Persistence of Klebsiella pneumoniae clones with OXA-48 or NDM carbapenemases causing bacteraemias in a Riyadh hospital

Mohamed H. Al-Agamy
, Atef M. Shibl
, Noura A. Elkhizzi
, Daniele Meunier
, Jane F. Turton
, David M. Livermore

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

We characterized nine carbapenem-resistant Klebsiella pneumoniae collected over 9 months during 2011 in Riyadh; 8 from Hospital A and 1 from Hospital B. Variable number tandem repeat (VNTR) defined three strains at Hospital A, each with 2 or 3 representatives recovered from separate patients over periods of 6–24 weeks; 2 strains had OXA-48 and 1 had NDM. The single isolate from Hospital B also had OXA-48 but was distinct by VNTR from the Hospital A strains. Two strains with OXA-48 were colistin resistant; the third included a colistin-resistant representative from a colistin-treated patient.

Original language	English
Pages (from-to)	214-216
Number of pages	3
Journal	Diagnostic Microbiology and Infectious Disease
Volume	76
Issue number	2
DOIs	https://doi.org/10.1016/j.diagmicrobio.2013.02.006
Publication status	Published - 1 Jun 2013

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10.1016/j.diagmicrobio.2013.02.006

Cite this

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title = "Persistence of Klebsiella pneumoniae clones with OXA-48 or NDM carbapenemases causing bacteraemias in a Riyadh hospital",

abstract = "We characterized nine carbapenem-resistant Klebsiella pneumoniae collected over 9 months during 2011 in Riyadh; 8 from Hospital A and 1 from Hospital B. Variable number tandem repeat (VNTR) defined three strains at Hospital A, each with 2 or 3 representatives recovered from separate patients over periods of 6–24 weeks; 2 strains had OXA-48 and 1 had NDM. The single isolate from Hospital B also had OXA-48 but was distinct by VNTR from the Hospital A strains. Two strains with OXA-48 were colistin resistant; the third included a colistin-resistant representative from a colistin-treated patient.",

author = "Al-Agamy, \{Mohamed H.\} and Shibl, \{Atef M.\} and Elkhizzi, \{Noura A.\} and Daniele Meunier and Turton, \{Jane F.\} and Livermore, \{David M.\}",

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T1 - Persistence of Klebsiella pneumoniae clones with OXA-48 or NDM carbapenemases causing bacteraemias in a Riyadh hospital

AU - Al-Agamy, Mohamed H.

AU - Shibl, Atef M.

AU - Elkhizzi, Noura A.

AU - Meunier, Daniele

AU - Turton, Jane F.

AU - Livermore, David M.

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AB - We characterized nine carbapenem-resistant Klebsiella pneumoniae collected over 9 months during 2011 in Riyadh; 8 from Hospital A and 1 from Hospital B. Variable number tandem repeat (VNTR) defined three strains at Hospital A, each with 2 or 3 representatives recovered from separate patients over periods of 6–24 weeks; 2 strains had OXA-48 and 1 had NDM. The single isolate from Hospital B also had OXA-48 but was distinct by VNTR from the Hospital A strains. Two strains with OXA-48 were colistin resistant; the third included a colistin-resistant representative from a colistin-treated patient.

U2 - 10.1016/j.diagmicrobio.2013.02.006

DO - 10.1016/j.diagmicrobio.2013.02.006

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JO - Diagnostic Microbiology and Infectious Disease

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