Phytochemical and antimicrobial investigation of latex from Euphorbia abyssinica Gmel

Fathy El-Fiky; Kaleab Asres; Simon Gibbons; Hala Hammoda; Jihau Badr; Shemsu Umer

doi:10.1177/1934578X0800300922

Phytochemical and antimicrobial investigation of latex from Euphorbia abyssinica Gmel

Fathy El-Fiky, Kaleab Asres, Simon Gibbons, Hala Hammoda, Jihau Badr, Shemsu Umer

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Phytochemical investigation of the latex of Euphorbia abyssinica Gmel (Euphorbiaceae) afforded a new hydroxy unsaturated fatty acid, 8(R)-hydroxy-dec-3(E)-en-oic acid (1), in addition to the four known compounds lupeol (2), beta-sitosterol (3), oleanolic acid (4) and beta-sitosterol-3-O-glucoside (5). The in vitro antibacterial and antifungal activities of the isolated compounds, as well as the total methanol extract, were studied against different micro-organisms; compound 1 displayed reasonable antifungal activities towards the tested fungi.

Original language	English
Pages (from-to)	1505-1508
Number of pages	4
Journal	Natural Product Communications
Volume	3
Issue number	9
DOIs	https://doi.org/10.1177/1934578X0800300922
Publication status	Published - 1 Sep 2008

Keywords

Euphorbia abyssinica Gmel.
Euphorbiaceae
8(R)-hydroxy-dec-3(E)-en-oic acid
antimicrobial activity
DITERPENES
FRACTION

Access to Document

10.1177/1934578X0800300922

Cite this

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title = "Phytochemical and antimicrobial investigation of latex from Euphorbia abyssinica Gmel",

abstract = "Phytochemical investigation of the latex of Euphorbia abyssinica Gmel (Euphorbiaceae) afforded a new hydroxy unsaturated fatty acid, 8(R)-hydroxy-dec-3(E)-en-oic acid (1), in addition to the four known compounds lupeol (2), beta-sitosterol (3), oleanolic acid (4) and beta-sitosterol-3-O-glucoside (5). The in vitro antibacterial and antifungal activities of the isolated compounds, as well as the total methanol extract, were studied against different micro-organisms; compound 1 displayed reasonable antifungal activities towards the tested fungi.",

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year = "2008",

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T1 - Phytochemical and antimicrobial investigation of latex from Euphorbia abyssinica Gmel

AU - El-Fiky, Fathy

AU - Asres, Kaleab

AU - Gibbons, Simon

AU - Hammoda, Hala

AU - Badr, Jihau

AU - Umer, Shemsu

PY - 2008/9/1

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N2 - Phytochemical investigation of the latex of Euphorbia abyssinica Gmel (Euphorbiaceae) afforded a new hydroxy unsaturated fatty acid, 8(R)-hydroxy-dec-3(E)-en-oic acid (1), in addition to the four known compounds lupeol (2), beta-sitosterol (3), oleanolic acid (4) and beta-sitosterol-3-O-glucoside (5). The in vitro antibacterial and antifungal activities of the isolated compounds, as well as the total methanol extract, were studied against different micro-organisms; compound 1 displayed reasonable antifungal activities towards the tested fungi.

AB - Phytochemical investigation of the latex of Euphorbia abyssinica Gmel (Euphorbiaceae) afforded a new hydroxy unsaturated fatty acid, 8(R)-hydroxy-dec-3(E)-en-oic acid (1), in addition to the four known compounds lupeol (2), beta-sitosterol (3), oleanolic acid (4) and beta-sitosterol-3-O-glucoside (5). The in vitro antibacterial and antifungal activities of the isolated compounds, as well as the total methanol extract, were studied against different micro-organisms; compound 1 displayed reasonable antifungal activities towards the tested fungi.

KW - Euphorbia abyssinica Gmel.

KW - Euphorbiaceae

KW - 8(R)-hydroxy-dec-3(E)-en-oic acid

KW - antimicrobial activity

KW - DITERPENES

KW - FRACTION

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DO - 10.1177/1934578X0800300922

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JO - Natural Product Communications

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