Phytochemical and antimicrobial investigation of latex from Euphorbia abyssinica Gmel

Fathy El-Fiky; Kaleab Asres; Simon Gibbons; Hala Hammoda; Jihau Badr; Shemsu Umer

doi:10.1177/1934578X0800300922

Phytochemical and antimicrobial investigation of latex from Euphorbia abyssinica Gmel

Fathy El-Fiky, Kaleab Asres, Simon Gibbons, Hala Hammoda, Jihau Badr, Shemsu Umer

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Phytochemical investigation of the latex of Euphorbia abyssinica Gmel (Euphorbiaceae) afforded a new hydroxy unsaturated fatty acid, 8(R)-hydroxy-dec-3(E)-en-oic acid (1), in addition to the four known compounds lupeol (2), beta-sitosterol (3), oleanolic acid (4) and beta-sitosterol-3-O-glucoside (5). The in vitro antibacterial and antifungal activities of the isolated compounds, as well as the total methanol extract, were studied against different micro-organisms; compound 1 displayed reasonable antifungal activities towards the tested fungi.

Original language	English
Pages (from-to)	1505-1508
Number of pages	4
Journal	Natural Product Communications
Volume	3
Issue number	9
DOIs	https://doi.org/10.1177/1934578X0800300922
Publication status	Published - 1 Sep 2008

Keywords

Euphorbia abyssinica Gmel.
Euphorbiaceae
8(R)-hydroxy-dec-3(E)-en-oic acid
antimicrobial activity
DITERPENES
FRACTION

Access to Document

10.1177/1934578X0800300922

Cite this

@article{da1f6dd34a694c6a830cccf1ddb3caac,

title = "Phytochemical and antimicrobial investigation of latex from Euphorbia abyssinica Gmel",

abstract = "Phytochemical investigation of the latex of Euphorbia abyssinica Gmel (Euphorbiaceae) afforded a new hydroxy unsaturated fatty acid, 8(R)-hydroxy-dec-3(E)-en-oic acid (1), in addition to the four known compounds lupeol (2), beta-sitosterol (3), oleanolic acid (4) and beta-sitosterol-3-O-glucoside (5). The in vitro antibacterial and antifungal activities of the isolated compounds, as well as the total methanol extract, were studied against different micro-organisms; compound 1 displayed reasonable antifungal activities towards the tested fungi.",

keywords = "Euphorbia abyssinica Gmel., Euphorbiaceae, 8(R)-hydroxy-dec-3(E)-en-oic acid, antimicrobial activity, DITERPENES, FRACTION",

author = "Fathy El-Fiky and Kaleab Asres and Simon Gibbons and Hala Hammoda and Jihau Badr and Shemsu Umer",

year = "2008",

month = sep,

day = "1",

doi = "10.1177/1934578X0800300922",

language = "English",

volume = "3",

pages = "1505--1508",

journal = "Natural Product Communications",

issn = "1934-578X",

publisher = "Sage Publications",

number = "9",

}

TY - JOUR

T1 - Phytochemical and antimicrobial investigation of latex from Euphorbia abyssinica Gmel

AU - El-Fiky, Fathy

AU - Asres, Kaleab

AU - Gibbons, Simon

AU - Hammoda, Hala

AU - Badr, Jihau

AU - Umer, Shemsu

PY - 2008/9/1

Y1 - 2008/9/1

N2 - Phytochemical investigation of the latex of Euphorbia abyssinica Gmel (Euphorbiaceae) afforded a new hydroxy unsaturated fatty acid, 8(R)-hydroxy-dec-3(E)-en-oic acid (1), in addition to the four known compounds lupeol (2), beta-sitosterol (3), oleanolic acid (4) and beta-sitosterol-3-O-glucoside (5). The in vitro antibacterial and antifungal activities of the isolated compounds, as well as the total methanol extract, were studied against different micro-organisms; compound 1 displayed reasonable antifungal activities towards the tested fungi.

AB - Phytochemical investigation of the latex of Euphorbia abyssinica Gmel (Euphorbiaceae) afforded a new hydroxy unsaturated fatty acid, 8(R)-hydroxy-dec-3(E)-en-oic acid (1), in addition to the four known compounds lupeol (2), beta-sitosterol (3), oleanolic acid (4) and beta-sitosterol-3-O-glucoside (5). The in vitro antibacterial and antifungal activities of the isolated compounds, as well as the total methanol extract, were studied against different micro-organisms; compound 1 displayed reasonable antifungal activities towards the tested fungi.

KW - Euphorbia abyssinica Gmel.

KW - Euphorbiaceae

KW - 8(R)-hydroxy-dec-3(E)-en-oic acid

KW - antimicrobial activity

KW - DITERPENES

KW - FRACTION

U2 - 10.1177/1934578X0800300922

DO - 10.1177/1934578X0800300922

M3 - Article

VL - 3

SP - 1505

EP - 1508

JO - Natural Product Communications

JF - Natural Product Communications

SN - 1934-578X

IS - 9

ER -