Phytochemical and antimicrobial investigation of latex from Euphorbia abyssinica Gmel

Fathy El-Fiky, Kaleab Asres, Simon Gibbons, Hala Hammoda, Jihau Badr, Shemsu Umer

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Phytochemical investigation of the latex of Euphorbia abyssinica Gmel (Euphorbiaceae) afforded a new hydroxy unsaturated fatty acid, 8(R)-hydroxy-dec-3(E)-en-oic acid (1), in addition to the four known compounds lupeol (2), beta-sitosterol (3), oleanolic acid (4) and beta-sitosterol-3-O-glucoside (5). The in vitro antibacterial and antifungal activities of the isolated compounds, as well as the total methanol extract, were studied against different micro-organisms; compound 1 displayed reasonable antifungal activities towards the tested fungi.

Original languageEnglish
Pages (from-to)1505-1508
Number of pages4
JournalNatural Product Communications
Issue number9
Publication statusPublished - 1 Sep 2008


  • Euphorbia abyssinica Gmel.
  • Euphorbiaceae
  • 8(R)-hydroxy-dec-3(E)-en-oic acid
  • antimicrobial activity

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