Pistachios increase serum antioxidants and lower serum oxidized-LDL in hypercholesterolemic adults

Colin D Kay, Sarah K Gebauer, Sheila G West, Penny M Kris-Etherton

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

Pistachios are high in lutein, beta-carotene, and gamma-tocopherol relative to other nuts; however, studies of the effects of pistachios on oxidative status are lacking. We conducted a randomized, crossover controlled-feeding study to evaluate 2 doses of pistachios on serum antioxidants and biomarkers of oxidative status in 28 hypercholesterolemic adults (LDL-cholesterol >or=2.86 mmol/L). Participants consumed 3 isoenergetic diets for 4 wk each after a 2-wk baseline Western diet. Experimental diets included a lower-fat control diet without pistachios (25% total fat) with 1 serving/d (i.e. 32-63 g/d; energy adjusted) of pistachios (1 PD; 10% energy from pistachios; 30% total fat) or with 2 servings/d (63-126 g/d; energy adjusted) of pistachios (2 PD; 20% energy from pistachios; 34% total fat). When participants consumed the pistachio-enriched diets, they had higher plasma lutein (P
Original languageEnglish
Pages (from-to)1093-1098
Number of pages6
JournalJournal of Nutrition
Volume140
Issue number6
DOIs
Publication statusPublished - Jun 2010

Keywords

  • Adult
  • Antioxidants
  • Biological Markers
  • Cross-Over Studies
  • Diet
  • Female
  • Humans
  • Hypercholesterolemia
  • Lipoproteins, LDL
  • Male
  • Middle Aged
  • Pistacia

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