Placebo controlled trial of clarithromycin in active Crohn's disease

K Leiper; K Martin; A Ellis; A J M Watson; A I Morris; J M Rhodes

doi:10.1111/j.1365-2036.2008.03661.x

Placebo controlled trial of clarithromycin in active Crohn's disease

K Leiper, K Martin, A Ellis, A J M Watson, A I Morris, J M Rhodes

Research output: Contribution to journal › Article › peer-review

47 Citations (Scopus)

Abstract

Crohn's disease is characterized by defective innate immune responses to intestinal bacteria. Clarithromycin is a broad-spectrum antibiotic that has good penetration into macrophages.

Original language	English
Pages (from-to)	1233-1239
Number of pages	7
Journal	Alimentary Pharmacology & Therapeutics
Volume	27
Issue number	12
DOIs	https://doi.org/10.1111/j.1365-2036.2008.03661.x
Publication status	Published - Jun 2008

Keywords

Adult
Anti-Bacterial Agents
Clarithromycin
Crohn Disease
Drug Administration Schedule
Female
Humans
Male
Placebos
Treatment Outcome

Access to Document

10.1111/j.1365-2036.2008.03661.x

Cite this

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title = "Placebo controlled trial of clarithromycin in active Crohn's disease",

abstract = "Crohn's disease is characterized by defective innate immune responses to intestinal bacteria. Clarithromycin is a broad-spectrum antibiotic that has good penetration into macrophages.",

keywords = "Adult, Anti-Bacterial Agents, Clarithromycin, Crohn Disease, Drug Administration Schedule, Female, Humans, Male, Placebos, Treatment Outcome",

author = "K Leiper and K Martin and A Ellis and Watson, {A J M} and Morris, {A I} and Rhodes, {J M}",

year = "2008",

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AU - Leiper, K

AU - Martin, K

AU - Ellis, A

AU - Watson, A J M

AU - Morris, A I

AU - Rhodes, J M

PY - 2008/6

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N2 - Crohn's disease is characterized by defective innate immune responses to intestinal bacteria. Clarithromycin is a broad-spectrum antibiotic that has good penetration into macrophages.

AB - Crohn's disease is characterized by defective innate immune responses to intestinal bacteria. Clarithromycin is a broad-spectrum antibiotic that has good penetration into macrophages.

KW - Adult

KW - Anti-Bacterial Agents

KW - Clarithromycin

KW - Crohn Disease

KW - Drug Administration Schedule

KW - Female

KW - Humans

KW - Male

KW - Placebos

KW - Treatment Outcome

U2 - 10.1111/j.1365-2036.2008.03661.x

DO - 10.1111/j.1365-2036.2008.03661.x

M3 - Article

C2 - 18315579

VL - 27

SP - 1233

EP - 1239

JO - Alimentary Pharmacology and Therapeutics

JF - Alimentary Pharmacology and Therapeutics

SN - 0269-2813

IS - 12

ER -