Planar chiral palladacycle precatalysts for asymmetric synthesis

Ross A. Arthurs, David L. Hughes, Christopher J. Richards

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Abstract

Chiral non-racemic palladacycles were employed as precatalysts for Pd(0) mediated asymmetric synthesis. Addition of HPAr2/base to a ferrocenyloxazoline planar chiral palladacycle resulted in ligand synthesis and palladium capture to give a bidentate Phosferrox/Pd(0) complex. A series of these complexes were generated in situ and applied successfully as catalysts for asymmetric allylic alkylation.

Original languageEnglish
Pages (from-to)5466-5472
Number of pages7
JournalOrganic & Biomolecular Chemistry
Volume18
Issue number28
Early online date2 Jul 2020
DOIs
Publication statusPublished - 28 Jul 2020

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