Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice

Julie Decock; Wouter Hendrickx; Sally Thirkettle; Ana Gutiérrez-Fernández; Stephen D Robinson; Dylan R Edwards

doi:10.1186/s13058-015-0545-8

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice

Julie Decock, Wouter Hendrickx, Sally Thirkettle, Ana Gutiérrez-Fernández, Stephen D Robinson, Dylan R Edwards

Research output: Contribution to journal › Article › peer-review

40 Citations (Scopus)

19 Downloads (Pure)

Abstract

Matrix metalloproteinase-8 (MMP-8; neutrophil collagenase) is an important regulator of innate immunity which has onco-suppressive actions in numerous tumor types.

Original language	English
Article number	38
Journal	Breast Cancer Research
Volume	17
Issue number	1
DOIs	https://doi.org/10.1186/s13058-015-0545-8
Publication status	Published - 14 Mar 2015

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1186/s13058-015-0545-8Licence: CC BY

Decock et al BCR 2015Final published version, 2.74 MBLicence: CC BY

Dylan Edwards
- Dylan.Edwardsuea.acuk
- Norwich Medical School - Emeritus Professor
- Norwich Institute for Healthy Aging - Member
- Metabolic Health - Member
- Cancer Studies - Member
Person: Honorary, Research Group Member, Research Centre Member
Stephen Robinson
- Stephen.Robinsonuea.acuk
- School of Biological Sciences - Research Leader
- Norwich Institute for Healthy Aging - Member
- Cells and Tissues - Member
Person: Research Group Member, Research Centre Member, Academic, Teaching and Research

Cite this

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title = "Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice",

abstract = "Matrix metalloproteinase-8 (MMP-8; neutrophil collagenase) is an important regulator of innate immunity which has onco-suppressive actions in numerous tumor types.",

author = "Julie Decock and Wouter Hendrickx and Sally Thirkettle and Ana Guti{\'e}rrez-Fern{\'a}ndez and Robinson, {Stephen D} and Edwards, {Dylan R}",

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AU - Decock, Julie

AU - Hendrickx, Wouter

AU - Thirkettle, Sally

AU - Gutiérrez-Fernández, Ana

AU - Robinson, Stephen D

AU - Edwards, Dylan R

N1 - © 2015 Decock et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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AB - Matrix metalloproteinase-8 (MMP-8; neutrophil collagenase) is an important regulator of innate immunity which has onco-suppressive actions in numerous tumor types.

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SN - 1465-542X

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Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice

Abstract

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Dylan Edwards

Stephen Robinson

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