Polymorphisms in the Apolipoprotein L1 gene and their effects on blood lipid and glucose levels in middle age males

Nigel M. Page; Estibaliz Olano-Martin; Christopher Lanaway; Rufus Turner; Anne Marie Minihane

doi:10.1007/BF02829955

Polymorphisms in the Apolipoprotein L1 gene and their effects on blood lipid and glucose levels in middle age males

Nigel M. Page, Estibaliz Olano-Martin, Christopher Lanaway, Rufus Turner, Anne Marie Minihane

Research output: Contribution to journal › Article

Abstract

Apolipoprotein L1 in plasma is associated with high-density lipoprotein. Novel APOL1 polymorphisms are investigated along with the association of two common haplotypes (Lysl66Glu, Ile244Met, Lys271Arg) with circulating lipid and glucose levels. Although the amino acid substitutions occur in the amphipathic alpha helices region involved in lipid binding, these substitutions were found not to independently account for variability in circulating lipid and glucose levels in 149 middle age males.

Original language	English
Pages (from-to)	133-135
Number of pages	3
Journal	Genes & Nutrition
Volume	1
Issue number	2
DOIs	https://doi.org/10.1007/BF02829955
Publication status	Published - Jun 2006

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10.1007/BF02829955

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title = "Polymorphisms in the Apolipoprotein L1 gene and their effects on blood lipid and glucose levels in middle age males",

abstract = "Apolipoprotein L1 in plasma is associated with high-density lipoprotein. Novel APOL1 polymorphisms are investigated along with the association of two common haplotypes (Lysl66Glu, Ile244Met, Lys271Arg) with circulating lipid and glucose levels. Although the amino acid substitutions occur in the amphipathic alpha helices region involved in lipid binding, these substitutions were found not to independently account for variability in circulating lipid and glucose levels in 149 middle age males.",

author = "Page, {Nigel M.} and Estibaliz Olano-Martin and Christopher Lanaway and Rufus Turner and Minihane, {Anne Marie}",

year = "2006",

month = jun,

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language = "English",

volume = "1",

pages = "133--135",

journal = "Genes & Nutrition",

issn = "1555-8932",

publisher = "BioMed Central",

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T1 - Polymorphisms in the Apolipoprotein L1 gene and their effects on blood lipid and glucose levels in middle age males

AU - Page, Nigel M.

AU - Olano-Martin, Estibaliz

AU - Lanaway, Christopher

AU - Turner, Rufus

AU - Minihane, Anne Marie

PY - 2006/6

Y1 - 2006/6

N2 - Apolipoprotein L1 in plasma is associated with high-density lipoprotein. Novel APOL1 polymorphisms are investigated along with the association of two common haplotypes (Lysl66Glu, Ile244Met, Lys271Arg) with circulating lipid and glucose levels. Although the amino acid substitutions occur in the amphipathic alpha helices region involved in lipid binding, these substitutions were found not to independently account for variability in circulating lipid and glucose levels in 149 middle age males.

AB - Apolipoprotein L1 in plasma is associated with high-density lipoprotein. Novel APOL1 polymorphisms are investigated along with the association of two common haplotypes (Lysl66Glu, Ile244Met, Lys271Arg) with circulating lipid and glucose levels. Although the amino acid substitutions occur in the amphipathic alpha helices region involved in lipid binding, these substitutions were found not to independently account for variability in circulating lipid and glucose levels in 149 middle age males.

U2 - 10.1007/BF02829955

DO - 10.1007/BF02829955

M3 - Article

VL - 1

SP - 133

EP - 135

JO - Genes & Nutrition

JF - Genes & Nutrition

SN - 1555-8932

IS - 2

ER -