Preoperative assessment of intracranial tumors with perfusion MR and a volumetric interpolated examination: a comparative study with DSA

Stephan G. Wetzel, Soonmee Cha, Meng Law, G. Johnson, John Golfinos, Peter Lee, Peter Kim Nelson

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25 Citations (Scopus)

Abstract

BACKGROUND AND PURPOSE: In evaluating intracranial tumors, a safe low-cost alternative that provides information similar to that of digital subtraction angiography (DSA) may be of interest. Our purpose was to determine the utility and limitations of a combined MR protocol in assessing (neo-) vascularity in intracranial tumors and their relation to adjacent vessels and to compare the results with those of DSA. METHODS: Twenty-two consecutive patients with an intracranial tumor who underwent preoperative stereoscopic DSA were examined with contrast-enhanced dynamic T2*-weighted perfusion MR imaging followed by a T1-weighted three-dimensional (3D) MR study (volumetric interpolated brain examination [VIBE]). The maximum relative cerebral blood volume (rCBV) of the tumor was compared with tumor vascularity at DSA. Critical vessel structures were defined in each patient, and VIBE images of these structures were compared with DSA findings. For full exploitation of the 3D data sets, maximum-intensity projection algorithms reconstructed in real time with any desired volume and orientation were used. RESULTS: Tumor blush scores at DSA were significantly correlated with the rCBV measurements (r = 0.75; P
Original languageEnglish
Pages (from-to)1767-1774
Number of pages8
JournalAmerican Journal of Neuroradiology
Volume23
Issue number10
Publication statusPublished - 2002

Keywords

  • Adult Aged Angiography, Digital Subtraction Blood Volume/*physiology Brain Neoplasms/*diagnosis/*physiopathology Cerebral Arteries/physiopathology/radiography Cerebral Cortex/*blood supply/*physiopathology/radiography Cerebral Veins/physiopathology/radiography Cerebrovascular Circulation/physiology Female Humans *Magnetic Resonance Angiography Male Middle Aged Neurologic Examination New York *Preoperative Care Recurrence Severity of Illness Index Statistics as Topic

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