PRKC-ζ Expression Promotes the Aggressive Phenotype of Human Prostate Cancer Cells and Is a Novel Target for Therapeutic Intervention

Sheng Yao; Alix Bee; Daniel Brewer; Andrew Dodson; Carol Beesley; Youqiang Ke; Laurence Ambroisine; Gabrielle Fisher; Heinrich Møller; Tim Dickinson; Patricia Gerard; Lu-Yu Lian; Janet Risk; Brian Lane; Paul Smith; Victor Reuter; Daniel Berney; Christine Gosden; Peter Scardino; Jack Cuzick; Mustafa B A Djamgoz; Colin Cooper; Christopher S Foster

doi:10.1177/1947601910376079

PRKC-ζ Expression Promotes the Aggressive Phenotype of Human Prostate Cancer Cells and Is a Novel Target for Therapeutic Intervention

Sheng Yao, Alix Bee, Daniel Brewer, Andrew Dodson, Carol Beesley, Youqiang Ke, Laurence Ambroisine, Gabrielle Fisher, Heinrich Møller, Tim Dickinson, Patricia Gerard, Lu-Yu Lian, Janet Risk, Brian Lane, Paul Smith, Victor Reuter, Daniel Berney, Christine Gosden, Peter Scardino, Jack CuzickMustafa B A Djamgoz, Colin Cooper, Christopher S Foster

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Abstract

We show protein kinase C-zeta (PKC-ζ) to be a novel predictive biomarker for survival from prostate cancer (P

Original language	English
Pages (from-to)	444-64
Number of pages	21
Journal	Genes & Cancer
Volume	1
Issue number	5
DOIs	https://doi.org/10.1177/1947601910376079
Publication status	Published - May 2010

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1177/1947601910376079

Cite this

Yao, S., Bee, A., Brewer, D., Dodson, A., Beesley, C., Ke, Y., Ambroisine, L., Fisher, G., Møller, H., Dickinson, T., Gerard, P., Lian, L-Y., Risk, J., Lane, B., Smith, P., Reuter, V., Berney, D., Gosden, C., Scardino, P., ... Foster, C. S. (2010). PRKC-ζ Expression Promotes the Aggressive Phenotype of Human Prostate Cancer Cells and Is a Novel Target for Therapeutic Intervention. Genes & Cancer, 1(5), 444-64. https://doi.org/10.1177/1947601910376079

Yao, Sheng ; Bee, Alix ; Brewer, Daniel ; Dodson, Andrew ; Beesley, Carol ; Ke, Youqiang ; Ambroisine, Laurence ; Fisher, Gabrielle ; Møller, Heinrich ; Dickinson, Tim ; Gerard, Patricia ; Lian, Lu-Yu ; Risk, Janet ; Lane, Brian ; Smith, Paul ; Reuter, Victor ; Berney, Daniel ; Gosden, Christine ; Scardino, Peter ; Cuzick, Jack ; Djamgoz, Mustafa B A ; Cooper, Colin ; Foster, Christopher S. / PRKC-ζ Expression Promotes the Aggressive Phenotype of Human Prostate Cancer Cells and Is a Novel Target for Therapeutic Intervention. In: Genes & Cancer. 2010 ; Vol. 1, No. 5. pp. 444-64.

@article{0458ee9882954e408983b55b875f5b8b,

title = "PRKC-ζ Expression Promotes the Aggressive Phenotype of Human Prostate Cancer Cells and Is a Novel Target for Therapeutic Intervention",

abstract = "We show protein kinase C-zeta (PKC-ζ) to be a novel predictive biomarker for survival from prostate cancer (P ",

author = "Sheng Yao and Alix Bee and Daniel Brewer and Andrew Dodson and Carol Beesley and Youqiang Ke and Laurence Ambroisine and Gabrielle Fisher and Heinrich M{\o}ller and Tim Dickinson and Patricia Gerard and Lu-Yu Lian and Janet Risk and Brian Lane and Paul Smith and Victor Reuter and Daniel Berney and Christine Gosden and Peter Scardino and Jack Cuzick and Djamgoz, {Mustafa B A} and Colin Cooper and Foster, {Christopher S}",

year = "2010",

month = may,

doi = "10.1177/1947601910376079",

language = "English",

volume = "1",

pages = "444--64",

journal = "Genes & Cancer",

issn = "1947-6019",

publisher = "Sage Publications",

number = "5",

}

Yao, S, Bee, A, Brewer, D, Dodson, A, Beesley, C, Ke, Y, Ambroisine, L, Fisher, G, Møller, H, Dickinson, T, Gerard, P, Lian, L-Y, Risk, J, Lane, B, Smith, P, Reuter, V, Berney, D, Gosden, C, Scardino, P, Cuzick, J, Djamgoz, MBA, Cooper, C & Foster, CS 2010, 'PRKC-ζ Expression Promotes the Aggressive Phenotype of Human Prostate Cancer Cells and Is a Novel Target for Therapeutic Intervention', Genes & Cancer, vol. 1, no. 5, pp. 444-64. https://doi.org/10.1177/1947601910376079

PRKC-ζ Expression Promotes the Aggressive Phenotype of Human Prostate Cancer Cells and Is a Novel Target for Therapeutic Intervention. / Yao, Sheng; Bee, Alix; Brewer, Daniel; Dodson, Andrew; Beesley, Carol; Ke, Youqiang; Ambroisine, Laurence; Fisher, Gabrielle; Møller, Heinrich; Dickinson, Tim; Gerard, Patricia; Lian, Lu-Yu; Risk, Janet; Lane, Brian; Smith, Paul; Reuter, Victor; Berney, Daniel; Gosden, Christine; Scardino, Peter; Cuzick, Jack; Djamgoz, Mustafa B A; Cooper, Colin; Foster, Christopher S.

In: Genes & Cancer, Vol. 1, No. 5, 05.2010, p. 444-64.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - PRKC-ζ Expression Promotes the Aggressive Phenotype of Human Prostate Cancer Cells and Is a Novel Target for Therapeutic Intervention

AU - Yao, Sheng

AU - Bee, Alix

AU - Brewer, Daniel

AU - Dodson, Andrew

AU - Beesley, Carol

AU - Ke, Youqiang

AU - Ambroisine, Laurence

AU - Fisher, Gabrielle

AU - Møller, Heinrich

AU - Dickinson, Tim

AU - Gerard, Patricia

AU - Lian, Lu-Yu

AU - Risk, Janet

AU - Lane, Brian

AU - Smith, Paul

AU - Reuter, Victor

AU - Berney, Daniel

AU - Gosden, Christine

AU - Scardino, Peter

AU - Cuzick, Jack

AU - Djamgoz, Mustafa B A

AU - Cooper, Colin

AU - Foster, Christopher S

PY - 2010/5

Y1 - 2010/5

N2 - We show protein kinase C-zeta (PKC-ζ) to be a novel predictive biomarker for survival from prostate cancer (P

AB - We show protein kinase C-zeta (PKC-ζ) to be a novel predictive biomarker for survival from prostate cancer (P

U2 - 10.1177/1947601910376079

DO - 10.1177/1947601910376079

M3 - Article

C2 - 21779455

VL - 1

SP - 444

EP - 464

JO - Genes & Cancer

JF - Genes & Cancer

SN - 1947-6019

IS - 5

ER -