Abstract
The stereochemical course of the hydroxylation of (S)-proline by proline 4-hydroxylase from Streptomyces griseoviridus P8648 has been investigated using (2S, 4S)-[4-2H1]-proline and (2S, 4R)-[4-2H1]-proline and found to occur with retention of stereochemistry at C-4 of proline.
Original language | English |
---|---|
Pages (from-to) | 7489-7492 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 34 |
Issue number | 46 |
DOIs | |
Publication status | Published - 12 Nov 1993 |