Prospective single-arm study of intraoperative radiotherapy for locally advanced or recurrent rectal cancer

Jennifer Tan; Alexander G. Heriot; Jack Mackay; Sylvia Van Dyk; Mathias A. B. Bressel; Chris D. Fox; Andrew C. Hui; A. Craig Lynch; Trevor Leong; Samuel Y. Ngan

doi:10.1111/1754-9485.12059

Prospective single-arm study of intraoperative radiotherapy for locally advanced or recurrent rectal cancer

Jennifer Tan
, Alexander G. Heriot
, Jack Mackay
, Sylvia Van Dyk
, Mathias A. B. Bressel
, Chris D. Fox
, Andrew C. Hui
, A. Craig Lynch
, Trevor Leong
, Samuel Y. Ngan

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

This study aims to evaluate the feasibility and outcomes of intraoperative radiotherapy (IORT) using high-dose-rate (HDR) brachytherapy for locally advanced or recurrent rectal cancers. Despite preoperative chemoradiation, patients with locally advanced or recurrent rectal cancers undergoing surgery remain at high risk of local recurrence. Intensification of radiation with IORT may improve local control.

Original language	English
Pages (from-to)	617-625
Number of pages	9
Journal	Journal of Medical Imaging and Radiation Oncology
Volume	57
Issue number	5
DOIs	https://doi.org/10.1111/1754-9485.12059
Publication status	Published - Oct 2013

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1111/1754-9485.12059

Cite this

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title = "Prospective single-arm study of intraoperative radiotherapy for locally advanced or recurrent rectal cancer",

abstract = "This study aims to evaluate the feasibility and outcomes of intraoperative radiotherapy (IORT) using high-dose-rate (HDR) brachytherapy for locally advanced or recurrent rectal cancers. Despite preoperative chemoradiation, patients with locally advanced or recurrent rectal cancers undergoing surgery remain at high risk of local recurrence. Intensification of radiation with IORT may improve local control.",

author = "Jennifer Tan and Heriot, \{Alexander G.\} and Jack Mackay and \{Van Dyk\}, Sylvia and Bressel, \{Mathias A. B.\} and Fox, \{Chris D.\} and Hui, \{Andrew C.\} and Lynch, \{A. Craig\} and Trevor Leong and Ngan, \{Samuel Y.\}",

note = "{\textcopyright} 2013 The Authors. Journal of Medical Imaging and Radiation Oncology {\textcopyright} 2013 The Royal Australian and New Zealand College of Radiologists.",

year = "2013",

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doi = "10.1111/1754-9485.12059",

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AU - Tan, Jennifer

AU - Heriot, Alexander G.

AU - Mackay, Jack

AU - Van Dyk, Sylvia

AU - Bressel, Mathias A. B.

AU - Fox, Chris D.

AU - Hui, Andrew C.

AU - Lynch, A. Craig

AU - Leong, Trevor

AU - Ngan, Samuel Y.

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N2 - This study aims to evaluate the feasibility and outcomes of intraoperative radiotherapy (IORT) using high-dose-rate (HDR) brachytherapy for locally advanced or recurrent rectal cancers. Despite preoperative chemoradiation, patients with locally advanced or recurrent rectal cancers undergoing surgery remain at high risk of local recurrence. Intensification of radiation with IORT may improve local control.

AB - This study aims to evaluate the feasibility and outcomes of intraoperative radiotherapy (IORT) using high-dose-rate (HDR) brachytherapy for locally advanced or recurrent rectal cancers. Despite preoperative chemoradiation, patients with locally advanced or recurrent rectal cancers undergoing surgery remain at high risk of local recurrence. Intensification of radiation with IORT may improve local control.

U2 - 10.1111/1754-9485.12059

DO - 10.1111/1754-9485.12059

M3 - Article

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SN - 1754-9485

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SP - 617

EP - 625

JO - Journal of Medical Imaging and Radiation Oncology

JF - Journal of Medical Imaging and Radiation Oncology

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