Protein voltammetry and spectroscopy: integrating approaches

Louise Male, Sophie Marritt, Ben C. Berks, Myles Cheesman, Jessica Van Wonderen, Simon J. George, Julea Butt

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)
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Abstract

Cyclic voltammetry readily visualizes the redox properties of many proteins. Net electron exchange between the protein and an electrode produces an electrical current that simultaneously quantitates and characterizes the underlying redox event(s). However, no direct information regarding the molecular origin, or consequences, of electron transfer is available. Integrating voltammetric and spectroscopic methods is one route to a more ‘holistic’ description of protein electron transfer. Here, we illustrate this approach with spectroelectrochemical studies of Rhodovulum sulfidophilum cytochrome c 2 and Escherichia coli cytochrome bd that employ electronic absorbance, infra-red and magnetic circular dichroism spectroscopies.
Original languageEnglish
Pages (from-to)107-111
Number of pages5
JournalTheoretical Chemistry Accounts: Theory, Computation, and Modeling
Volume119
Issue number1-3
DOIs
Publication statusPublished - 9 Jan 2007

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