Randomized trial of effects of continuous combined HRT on markers of lipids and coagulation in women with acute coronary syndromes: WHISP Pilot Study

Peter Collins, Marcus Flather, Belinda Lees, Rebecca Mister, Anthony J Proudler, John C Stevenson, WHISP (Women's Hormone Intervention Secondary Prevention Study) Pilot Study Investigators

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)


Randomized trials have not demonstrated coronary heart disease benefit from hormone replacement therapy (HRT). We hypothesized that low-dose HRT may avoid harm.
Original languageEnglish
Pages (from-to)2046-53
Number of pages8
JournalEuropean Heart Journal
Issue number17
Publication statusPublished - Sep 2006


  • Aged
  • Biological Markers
  • Blood Coagulation
  • Coronary Disease
  • Drug Combinations
  • Enzyme-Linked Immunosorbent Assay
  • Estradiol
  • Factor VII
  • Feasibility Studies
  • Female
  • Fibrinolysis
  • Hemostasis
  • Hormone Replacement Therapy
  • Humans
  • Lipids
  • Middle Aged
  • Norethindrone
  • Pilot Projects

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