Real-time methylomic aberrations during initiation and progression of induced human mammary epithelial cell tumorigenesis

Natalie E Mitchell; MacKenzie L Wilson; Molly S Bray; David K Crossman; Trygve O Tollefsbol

doi:10.2217/epi.13.6

Real-time methylomic aberrations during initiation and progression of induced human mammary epithelial cell tumorigenesis

Natalie E Mitchell, MacKenzie L Wilson, Molly S Bray, David K Crossman, Trygve O Tollefsbol

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Neoplastic transformation provides one of the few existing opportunities to analyze molecular changes in real time during the initiation and progression of breast cancer.

Original language	English
Pages (from-to)	155-165
Number of pages	11
Journal	Epigenomics
Volume	5
Issue number	2
DOIs	https://doi.org/10.2217/epi.13.6
Publication status	Published - Apr 2013

Keywords

Breast Neoplasms
Cell Dedifferentiation
Cell Line, Tumor
Cell Transformation, Neoplastic
CpG Islands
DNA Methylation
Epigenesis, Genetic
Female
Genome, Human
Humans
Mammary Glands, Human
Nuclear Reprogramming

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.2217/epi.13.6

Cite this

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title = "Real-time methylomic aberrations during initiation and progression of induced human mammary epithelial cell tumorigenesis",

abstract = "Neoplastic transformation provides one of the few existing opportunities to analyze molecular changes in real time during the initiation and progression of breast cancer.",

keywords = "Breast Neoplasms, Cell Dedifferentiation, Cell Line, Tumor, Cell Transformation, Neoplastic, CpG Islands, DNA Methylation, Epigenesis, Genetic, Female, Genome, Human, Humans, Mammary Glands, Human, Nuclear Reprogramming",

author = "Mitchell, {Natalie E} and Wilson, {MacKenzie L} and Bray, {Molly S} and Crossman, {David K} and Tollefsbol, {Trygve O}",

year = "2013",

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AU - Mitchell, Natalie E

AU - Wilson, MacKenzie L

AU - Bray, Molly S

AU - Crossman, David K

AU - Tollefsbol, Trygve O

PY - 2013/4

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AB - Neoplastic transformation provides one of the few existing opportunities to analyze molecular changes in real time during the initiation and progression of breast cancer.

KW - Breast Neoplasms

KW - Cell Dedifferentiation

KW - Cell Line, Tumor

KW - Cell Transformation, Neoplastic

KW - CpG Islands

KW - DNA Methylation

KW - Epigenesis, Genetic

KW - Female

KW - Genome, Human

KW - Humans

KW - Mammary Glands, Human

KW - Nuclear Reprogramming

U2 - 10.2217/epi.13.6

DO - 10.2217/epi.13.6

M3 - Article

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JO - Epigenomics

JF - Epigenomics

SN - 1750-1911

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