Redox-active ferrocene-modified Cowpea mosaic virus nanoparticles

Alaa A. A. Aljabali, J. Elaine Barclay, Julea Butt, George P. Lomonossoff, David J. Evans

Research output: Contribution to journalArticlepeer-review

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Abstract

A naturally occurring nanoparticle, the plant virus Cowpea mosaic virus, can be decorated with ferrocene derivatives, of various linker lengths with amine and carboxylategroups, on the external surface using a range of conjugation strategies. The multiple, organometallic, redox-active ferrocene moieties on the outer surface of the virus are electrochemically independent with reduction potentials that span a potential window of 0.16 V that are dependent on the site of modification and the nature of the ferrocene derivative. The number of ferrocenes coupled to each virus ranges from about 100 to 240 depending upon the conjugation site and the linker length and these redox active units can provide multielectron reservoirs.
Original languageEnglish
Pages (from-to)7569
Number of pages1
JournalDalton Transactions
Volume39
Issue number32
DOIs
Publication statusPublished - 2010

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