Reduced myocardial velocities of left ventricular long-axis contraction identify both systolic and diastolic heart failure-a comparison with brain natriuretic peptide

Dragos Vinereanu, Pitt O Lim, Michael P Frenneaux, Alan G Fraser

Research output: Contribution to journalArticlepeer-review

77 Citations (Scopus)


Echocardiographic diagnosis of radial fractional shortening or global ejection fraction fails to diagnose all patients with heart failure; about 40%, with apparently normal global systolic function, will have elevated brain natriuretic peptide (BNP) concentrations and "pure" diastolic dysfunction. Screening methods do not include assessment of left ventricular (LV) longitudinal function, however, which is a more sensitive marker of subclinical disease.
Original languageEnglish
Pages (from-to)512-9
Number of pages8
JournalEuropean Journal of Heart Failure
Issue number4
Publication statusPublished - Jun 2005


  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Diastole
  • Female
  • Heart Failure
  • Humans
  • Male
  • Middle Aged
  • Myocardial Contraction
  • Natriuretic Peptide, Brain
  • ROC Curve
  • Sensitivity and Specificity
  • Stroke Volume
  • Systole
  • Ultrasonography, Doppler
  • Ventricular Dysfunction, Left

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