Relative effects of two different enoxaparin regimens as comparators against newer oral anticoagulants: meta-analysis and adjusted indirect comparison

Chun Shing Kwok; Shiva Pradhan; Jessica Ka-yan Yeong; Yoon K Loke

doi:10.1378/chest.12-2634

Relative effects of two different enoxaparin regimens as comparators against newer oral anticoagulants: meta-analysis and adjusted indirect comparison

Chun Shing Kwok, Shiva Pradhan, Jessica Ka-yan Yeong, Yoon K Loke

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Two different regimens of enoxaparin (40 mg once daily or 30 mg bid) have been used as control arms in trials of new oral anticoagulants. The choice of enoxaparin comparator may influence the perceived relative efficacy and safety of the newer agents, and we aimed to identify any significant differences between the two enoxaparin regimens.

Original language	English
Pages (from-to)	593-600
Number of pages	8
Journal	Chest
Volume	144
Issue number	2
DOIs	https://doi.org/10.1378/chest.12-2634
Publication status	Published - Aug 2013

Keywords

Administration, Oral
Anticoagulants
Arthroplasty, Replacement, Hip
Arthroplasty, Replacement, Knee
Benzimidazoles
Enoxaparin
Humans
Morpholines
Pyrazoles
Pyridones
Randomized Controlled Trials as Topic
Thiophenes
Venous Thromboembolism
beta-Alanine

Access to Document

10.1378/chest.12-2634

Cite this

@article{7310a6a141ac4098be7ee64450087e3e,

title = "Relative effects of two different enoxaparin regimens as comparators against newer oral anticoagulants: meta-analysis and adjusted indirect comparison",

abstract = "Two different regimens of enoxaparin (40 mg once daily or 30 mg bid) have been used as control arms in trials of new oral anticoagulants. The choice of enoxaparin comparator may influence the perceived relative efficacy and safety of the newer agents, and we aimed to identify any significant differences between the two enoxaparin regimens.",

keywords = "Administration, Oral, Anticoagulants, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Benzimidazoles, Enoxaparin, Humans, Morpholines, Pyrazoles, Pyridones, Randomized Controlled Trials as Topic, Thiophenes, Venous Thromboembolism, beta-Alanine",

author = "Kwok, {Chun Shing} and Shiva Pradhan and Yeong, {Jessica Ka-yan} and Loke, {Yoon K}",

year = "2013",

month = aug,

doi = "10.1378/chest.12-2634",

language = "English",

volume = "144",

pages = "593--600",

journal = "Chest",

issn = "0012-3692",

publisher = "American College of Chest Physicians",

number = "2",

}

TY - JOUR

T1 - Relative effects of two different enoxaparin regimens as comparators against newer oral anticoagulants

T2 - meta-analysis and adjusted indirect comparison

AU - Kwok, Chun Shing

AU - Pradhan, Shiva

AU - Yeong, Jessica Ka-yan

AU - Loke, Yoon K

PY - 2013/8

Y1 - 2013/8

N2 - Two different regimens of enoxaparin (40 mg once daily or 30 mg bid) have been used as control arms in trials of new oral anticoagulants. The choice of enoxaparin comparator may influence the perceived relative efficacy and safety of the newer agents, and we aimed to identify any significant differences between the two enoxaparin regimens.

AB - Two different regimens of enoxaparin (40 mg once daily or 30 mg bid) have been used as control arms in trials of new oral anticoagulants. The choice of enoxaparin comparator may influence the perceived relative efficacy and safety of the newer agents, and we aimed to identify any significant differences between the two enoxaparin regimens.

KW - Administration, Oral

KW - Anticoagulants

KW - Arthroplasty, Replacement, Hip

KW - Arthroplasty, Replacement, Knee

KW - Benzimidazoles

KW - Enoxaparin

KW - Humans

KW - Morpholines

KW - Pyrazoles

KW - Pyridones

KW - Randomized Controlled Trials as Topic

KW - Thiophenes

KW - Venous Thromboembolism

KW - beta-Alanine

U2 - 10.1378/chest.12-2634

DO - 10.1378/chest.12-2634

M3 - Article

C2 - 23519234

VL - 144

SP - 593

EP - 600

JO - Chest

JF - Chest

SN - 0012-3692

IS - 2

ER -