Risk of iron overload in carriers of genetic mutations associated with hereditary haemochromatosis: UK Food Standards Agency workshop

Mamta Singh; Margaret Ashwell; Peter Sanderson; Janet Cade; Jennifer Moreton; Susan Fairweather-Tait; Mark Roe; Joannes J. M. Marx; Mark Worwood; James D. Cook

doi:10.1079/BJN20061892

Risk of iron overload in carriers of genetic mutations associated with hereditary haemochromatosis: UK Food Standards Agency workshop

Mamta Singh, Margaret Ashwell, Peter Sanderson, Janet Cade, Jennifer Moreton, Susan Fairweather-Tait, Mark Roe, Joannes J. M. Marx, Mark Worwood, James D. Cook

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

The UK Food Standards Agency convened a group of expert scientists to review current research investigating diet and carriers of genetic mutations associated with hereditary haemochromatosis. The workshop concluded that individuals who are heterozygous for the C282Y mutation of the HFE gene do not appear to respond abnormally to dietary Fe and therefore do not need to change their diet to prevent accumulation of body Fe.

Original language	English
Pages (from-to)	770-773
Number of pages	4
Journal	British Journal of Nutrition
Volume	96
Issue number	4
DOIs	https://doi.org/10.1079/BJN20061892
Publication status	Published - Oct 2006

Keywords

Atherosclerosis
Diet
Genetic Predisposition to Disease
Hemochromatosis
Heterozygote
Histocompatibility Antigens Class I
Humans
Iron Overload
Iron, Dietary
Membrane Proteins
Mutation

Access to Document

10.1079/BJN20061892

Cite this

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title = "Risk of iron overload in carriers of genetic mutations associated with hereditary haemochromatosis: UK Food Standards Agency workshop",

abstract = "The UK Food Standards Agency convened a group of expert scientists to review current research investigating diet and carriers of genetic mutations associated with hereditary haemochromatosis. The workshop concluded that individuals who are heterozygous for the C282Y mutation of the HFE gene do not appear to respond abnormally to dietary Fe and therefore do not need to change their diet to prevent accumulation of body Fe.",

keywords = "Atherosclerosis, Diet, Genetic Predisposition to Disease, Hemochromatosis, Heterozygote, Histocompatibility Antigens Class I, Humans, Iron Overload, Iron, Dietary, Membrane Proteins, Mutation",

author = "Mamta Singh and Margaret Ashwell and Peter Sanderson and Janet Cade and Jennifer Moreton and Susan Fairweather-Tait and Mark Roe and Marx, {Joannes J. M.} and Mark Worwood and Cook, {James D.}",

year = "2006",

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doi = "10.1079/BJN20061892",

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volume = "96",

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journal = "British Journal of Nutrition",

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T1 - Risk of iron overload in carriers of genetic mutations associated with hereditary haemochromatosis: UK Food Standards Agency workshop

AU - Singh, Mamta

AU - Ashwell, Margaret

AU - Sanderson, Peter

AU - Cade, Janet

AU - Moreton, Jennifer

AU - Fairweather-Tait, Susan

AU - Roe, Mark

AU - Marx, Joannes J. M.

AU - Worwood, Mark

AU - Cook, James D.

PY - 2006/10

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AB - The UK Food Standards Agency convened a group of expert scientists to review current research investigating diet and carriers of genetic mutations associated with hereditary haemochromatosis. The workshop concluded that individuals who are heterozygous for the C282Y mutation of the HFE gene do not appear to respond abnormally to dietary Fe and therefore do not need to change their diet to prevent accumulation of body Fe.

KW - Atherosclerosis

KW - Diet

KW - Genetic Predisposition to Disease

KW - Hemochromatosis

KW - Heterozygote

KW - Histocompatibility Antigens Class I

KW - Humans

KW - Iron Overload

KW - Iron, Dietary

KW - Membrane Proteins

KW - Mutation

U2 - 10.1079/BJN20061892

DO - 10.1079/BJN20061892

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JO - British Journal of Nutrition

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SN - 0007-1145

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