Risk of iron overload in carriers of genetic mutations associated with hereditary haemochromatosis: UK Food Standards Agency workshop

Mamta Singh, Margaret Ashwell, Peter Sanderson, Janet Cade, Jennifer Moreton, Susan Fairweather-Tait, Mark Roe, Joannes J M Marx, Mark Worwood, James D Cook

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

The UK Food Standards Agency convened a group of expert scientists to review current research investigating diet and carriers of genetic mutations associated with hereditary haemochromatosis. The workshop concluded that individuals who are heterozygous for the C282Y mutation of the HFE gene do not appear to respond abnormally to dietary Fe and therefore do not need to change their diet to prevent accumulation of body Fe.
Original languageEnglish
Pages (from-to)770-773
Number of pages4
JournalBritish Journal of Nutrition
Volume96
Issue number4
Publication statusPublished - Oct 2006

Keywords

  • Atherosclerosis
  • Diet
  • Genetic Predisposition to Disease
  • Hemochromatosis
  • Heterozygote
  • Histocompatibility Antigens Class I
  • Humans
  • Iron Overload
  • Iron, Dietary
  • Membrane Proteins
  • Mutation

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