Rotavirus G and P genotypes in rural Ghana

Richard H. Asmah, Jon Green, George E. Armah, Chris I. Gallimore, Jim J. Gray, Miren Iturriza-Gómara, Francis Anto, Abraham Oduro, Fred N. Binka, David W. G. Brown, Felicity Cutts

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Abstract

An epidemiological study of rotavirus infection was conducted on specimens collected from patients with gastroenteritis and domiciled in the rural Upper Eastern Region of Ghana during 1998. Fifty isolates, randomly selected from 165 human group A rotavirus-positive samples, were G and P characterized by a reverse transcription (RT)-PCR assay using a seminested multiplex method. Rotaviruses of the G3 genotype were found to be the predominant strain (78%), followed by G2 (14%) and G1 (2%). Mixed infections, as shown by combinations of G3 and G2 (4%) and G3 and G1 (2%), were also observed. P typing showed P[4] (72.34%) to be the prevalent strain, followed by P[6] (21.3%), P[8] (2.13%), and a combination of P[4] and P[6] (4.3%).
Original languageEnglish
Pages (from-to)1981-1984
Number of pages4
JournalJournal of Clinical Microbiology
Volume39
Issue number5
DOIs
Publication statusPublished - 2001

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