Sarcopenia with limited mobility: An international consensus

John E. Morley; Angela Marie Abbatecola; Josep M. Argiles; Vickie Baracos; Juergen Bauer; Shalender Bhasin; Tommy Cederholm; Andrew J. Stewart Coats; Steven R. Cummings; William J. Evans; Kenneth Fearon; Luigi Ferrucci; Roger A. Fielding; Jack M. Guralnik; Tamara B. Harris; Akio Inui; Kamyar Kalantar-Zadeh; Bridget-Anne Kirwan; Giovanni Mantovani; Maurizio Muscaritoli; Anne B. Newman; Filippo Rossi-Fanelli; Giuseppe M. C. Rosano; Ronenn Roubenoff; Morris Schambelan; Gerald H. Sokol; Thomas W. Storer; Bruno Vellas; Stephan von Haehling; Shing-Shing Yeh; Stefan D. Anker

doi:10.1016/j.jamda.2011.04.014

Sarcopenia with limited mobility: An international consensus

John E. Morley, Angela Marie Abbatecola, Josep M. Argiles, Vickie Baracos, Juergen Bauer, Shalender Bhasin, Tommy Cederholm, Andrew J. Stewart Coats, Steven R. Cummings, William J. Evans, Kenneth Fearon, Luigi Ferrucci, Roger A. Fielding, Jack M. Guralnik, Tamara B. Harris, Akio Inui, Kamyar Kalantar-Zadeh, Bridget-Anne Kirwan, Giovanni Mantovani, Maurizio MuscaritoliAnne B. Newman, Filippo Rossi-Fanelli, Giuseppe M. C. Rosano, Ronenn Roubenoff, Morris Schambelan, Gerald H. Sokol, Thomas W. Storer, Bruno Vellas, Stephan von Haehling, Shing-Shing Yeh, Stefan D. Anker

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Abstract

A consensus conference convened by the Society of Sarcopenia, Cachexia and Wasting Disorders has concluded that "Sarcopenia, ie, reduced muscle mass, with limited mobility" should be considered an important clinical entity and that most older persons should be screened for this condition. "Sarcopenia with limited mobility" is defined as a person with muscle loss whose walking speed is equal to or less than 1 m/s or who walks less than 400 m during a 6-minute walk, and who has a lean appendicular mass corrected for height squared of 2 standard deviations or more below the mean of healthy persons between 20 and 30 years of age of the same ethnic group. The limitation in mobility should not clearly be a result of otherwise defined specific diseases of muscle, peripheral vascular disease with intermittent claudication, central and peripheral nervous system disorders, or cachexia. Clinically significant interventions are defined as an increase in the 6-minute walk of at least 50 meters or an increase of walking speed of at least 0.1 m/s.

Original language	English
Pages (from-to)	403-409
Number of pages	7
Journal	Journal of the American Medical Directors Association
Volume	12
Issue number	6
DOIs	https://doi.org/10.1016/j.jamda.2011.04.014
Publication status	Published - Jul 2011

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10.1016/j.jamda.2011.04.014

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Morley, J. E., Abbatecola, A. M., Argiles, J. M., Baracos, V., Bauer, J., Bhasin, S., Cederholm, T., Coats, A. J. S., Cummings, S. R., Evans, W. J., Fearon, K., Ferrucci, L., Fielding, R. A., Guralnik, J. M., Harris, T. B., Inui, A., Kalantar-Zadeh, K., Kirwan, B-A., Mantovani, G., ... Anker, S. D. (2011). Sarcopenia with limited mobility: An international consensus. Journal of the American Medical Directors Association, 12(6), 403-409. https://doi.org/10.1016/j.jamda.2011.04.014

@article{42c7969481d94d81bdd4b3d5fa7d7ba9,

title = "Sarcopenia with limited mobility: An international consensus",

abstract = "A consensus conference convened by the Society of Sarcopenia, Cachexia and Wasting Disorders has concluded that {"}Sarcopenia, ie, reduced muscle mass, with limited mobility{"} should be considered an important clinical entity and that most older persons should be screened for this condition. {"}Sarcopenia with limited mobility{"} is defined as a person with muscle loss whose walking speed is equal to or less than 1 m/s or who walks less than 400 m during a 6-minute walk, and who has a lean appendicular mass corrected for height squared of 2 standard deviations or more below the mean of healthy persons between 20 and 30 years of age of the same ethnic group. The limitation in mobility should not clearly be a result of otherwise defined specific diseases of muscle, peripheral vascular disease with intermittent claudication, central and peripheral nervous system disorders, or cachexia. Clinically significant interventions are defined as an increase in the 6-minute walk of at least 50 meters or an increase of walking speed of at least 0.1 m/s.",

author = "Morley, {John E.} and Abbatecola, {Angela Marie} and Argiles, {Josep M.} and Vickie Baracos and Juergen Bauer and Shalender Bhasin and Tommy Cederholm and Coats, {Andrew J. Stewart} and Cummings, {Steven R.} and Evans, {William J.} and Kenneth Fearon and Luigi Ferrucci and Fielding, {Roger A.} and Guralnik, {Jack M.} and Harris, {Tamara B.} and Akio Inui and Kamyar Kalantar-Zadeh and Bridget-Anne Kirwan and Giovanni Mantovani and Maurizio Muscaritoli and Newman, {Anne B.} and Filippo Rossi-Fanelli and Rosano, {Giuseppe M. C.} and Ronenn Roubenoff and Morris Schambelan and Sokol, {Gerald H.} and Storer, {Thomas W.} and Bruno Vellas and {von Haehling}, Stephan and Shing-Shing Yeh and Anker, {Stefan D.}",

year = "2011",

month = jul,

doi = "10.1016/j.jamda.2011.04.014",

language = "English",

volume = "12",

pages = "403--409",

journal = "Journal of the American Medical Directors Association",

issn = "1525-8610",

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Morley, JE, Abbatecola, AM, Argiles, JM, Baracos, V, Bauer, J, Bhasin, S, Cederholm, T, Coats, AJS, Cummings, SR, Evans, WJ, Fearon, K, Ferrucci, L, Fielding, RA, Guralnik, JM, Harris, TB, Inui, A, Kalantar-Zadeh, K, Kirwan, B-A, Mantovani, G, Muscaritoli, M, Newman, AB, Rossi-Fanelli, F, Rosano, GMC, Roubenoff, R, Schambelan, M, Sokol, GH, Storer, TW, Vellas, B, von Haehling, S, Yeh, S-S & Anker, SD 2011, 'Sarcopenia with limited mobility: An international consensus', Journal of the American Medical Directors Association, vol. 12, no. 6, pp. 403-409. https://doi.org/10.1016/j.jamda.2011.04.014

TY - JOUR

T1 - Sarcopenia with limited mobility: An international consensus

AU - Morley, John E.

AU - Abbatecola, Angela Marie

AU - Argiles, Josep M.

AU - Baracos, Vickie

AU - Bauer, Juergen

AU - Bhasin, Shalender

AU - Cederholm, Tommy

AU - Coats, Andrew J. Stewart

AU - Cummings, Steven R.

AU - Evans, William J.

AU - Fearon, Kenneth

AU - Ferrucci, Luigi

AU - Fielding, Roger A.

AU - Guralnik, Jack M.

AU - Harris, Tamara B.

AU - Inui, Akio

AU - Kalantar-Zadeh, Kamyar

AU - Kirwan, Bridget-Anne

AU - Mantovani, Giovanni

AU - Muscaritoli, Maurizio

AU - Newman, Anne B.

AU - Rossi-Fanelli, Filippo

AU - Rosano, Giuseppe M. C.

AU - Roubenoff, Ronenn

AU - Schambelan, Morris

AU - Sokol, Gerald H.

AU - Storer, Thomas W.

AU - Vellas, Bruno

AU - von Haehling, Stephan

AU - Yeh, Shing-Shing

AU - Anker, Stefan D.

PY - 2011/7

Y1 - 2011/7

N2 - A consensus conference convened by the Society of Sarcopenia, Cachexia and Wasting Disorders has concluded that "Sarcopenia, ie, reduced muscle mass, with limited mobility" should be considered an important clinical entity and that most older persons should be screened for this condition. "Sarcopenia with limited mobility" is defined as a person with muscle loss whose walking speed is equal to or less than 1 m/s or who walks less than 400 m during a 6-minute walk, and who has a lean appendicular mass corrected for height squared of 2 standard deviations or more below the mean of healthy persons between 20 and 30 years of age of the same ethnic group. The limitation in mobility should not clearly be a result of otherwise defined specific diseases of muscle, peripheral vascular disease with intermittent claudication, central and peripheral nervous system disorders, or cachexia. Clinically significant interventions are defined as an increase in the 6-minute walk of at least 50 meters or an increase of walking speed of at least 0.1 m/s.

AB - A consensus conference convened by the Society of Sarcopenia, Cachexia and Wasting Disorders has concluded that "Sarcopenia, ie, reduced muscle mass, with limited mobility" should be considered an important clinical entity and that most older persons should be screened for this condition. "Sarcopenia with limited mobility" is defined as a person with muscle loss whose walking speed is equal to or less than 1 m/s or who walks less than 400 m during a 6-minute walk, and who has a lean appendicular mass corrected for height squared of 2 standard deviations or more below the mean of healthy persons between 20 and 30 years of age of the same ethnic group. The limitation in mobility should not clearly be a result of otherwise defined specific diseases of muscle, peripheral vascular disease with intermittent claudication, central and peripheral nervous system disorders, or cachexia. Clinically significant interventions are defined as an increase in the 6-minute walk of at least 50 meters or an increase of walking speed of at least 0.1 m/s.

U2 - 10.1016/j.jamda.2011.04.014

DO - 10.1016/j.jamda.2011.04.014

M3 - Article

VL - 12

SP - 403

EP - 409

JO - Journal of the American Medical Directors Association

JF - Journal of the American Medical Directors Association

SN - 1525-8610

IS - 6

ER -