Seasonal variation in 25(OH)D at Aberdeen (57°N) and bone health indicators- Could holidays in the sun and cod liver oil supplements alleviate deficiency?

Alexandra Mavroeidi; Lorna Aucott; Alison J. Black; William D. Fraser; David M. Reid; Helen M. Macdonald

doi:10.1371/journal.pone.0053381

Seasonal variation in 25(OH)D at Aberdeen (57°N) and bone health indicators- Could holidays in the sun and cod liver oil supplements alleviate deficiency?

Alexandra Mavroeidi, Lorna Aucott, Alison J. Black, William D. Fraser, David M. Reid, Helen M. Macdonald

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

10 Downloads (Pure)

Abstract

Vitamin D has been linked with many health outcomes. The aim of this longitudinal study, was to assess predictors of seasonal variation of 25-hydroxy-vitamin D (25(OH)D) (including use of supplements and holidays in sunny destinations) at a northerly latitude in the UK (57°N) in relation to bone health indicators. 365 healthy postmenopausal women (mean age 62.0 y (SD 1.4)) had 25(OH)D measurements by immunoassay, serum C-telopeptide (CTX), estimates of sunlight exposure (badges of polysulphone film), information regarding holidays in sunny destinations, and diet (from food diaries, including use of supplements such as cod liver oil (CLO)) at fixed 3-monthly intervals over 15 months (subject retention 88%) with an additional 25(OH)D assessment in spring 2008. Bone mineral density (BMD) at the lumbar spine (LS) and dual hip was measured in autumn 2006 and spring 2007 (Lunar I-DXA). Deficiency prevalence (25(OH)D

Original language	English
Article number	e53381
Journal	PLoS One
Volume	8
Issue number	1
DOIs	https://doi.org/10.1371/journal.pone.0053381
Publication status	Published - 8 Jan 2013

Keywords

Absorptiometry, Photon
Bone Density
Bone and Bones
Cod Liver Oil
Collagen Type I
Dietary Supplements
Female
Great Britain
Hip
Holidays
Humans
Longitudinal Studies
Lumbosacral Region
Middle Aged
Parathyroid Hormone
Peptides
Postmenopause
Seasons
Sunlight
Vitamin D
Vitamin D Deficiency

Access to Document

10.1371/journal.pone.0053381Licence: CC BY

Mavroeidi_etal_2013_plosone
© 2013 Mavroeidi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Final published version, 246 KBLicence: CC BY

Cite this

@article{709d873df7c24f51b480fea4deadfeb5,

title = "Seasonal variation in 25(OH)D at Aberdeen (57°N) and bone health indicators- Could holidays in the sun and cod liver oil supplements alleviate deficiency?",

abstract = "Vitamin D has been linked with many health outcomes. The aim of this longitudinal study, was to assess predictors of seasonal variation of 25-hydroxy-vitamin D (25(OH)D) (including use of supplements and holidays in sunny destinations) at a northerly latitude in the UK (57°N) in relation to bone health indicators. 365 healthy postmenopausal women (mean age 62.0 y (SD 1.4)) had 25(OH)D measurements by immunoassay, serum C-telopeptide (CTX), estimates of sunlight exposure (badges of polysulphone film), information regarding holidays in sunny destinations, and diet (from food diaries, including use of supplements such as cod liver oil (CLO)) at fixed 3-monthly intervals over 15 months (subject retention 88%) with an additional 25(OH)D assessment in spring 2008. Bone mineral density (BMD) at the lumbar spine (LS) and dual hip was measured in autumn 2006 and spring 2007 (Lunar I-DXA). Deficiency prevalence (25(OH)D",

keywords = "Absorptiometry, Photon, Bone Density, Bone and Bones, Cod Liver Oil, Collagen Type I, Dietary Supplements, Female, Great Britain, Hip, Holidays, Humans, Longitudinal Studies, Lumbosacral Region, Middle Aged, Parathyroid Hormone, Peptides, Postmenopause, Seasons, Sunlight, Vitamin D, Vitamin D Deficiency",

author = "Alexandra Mavroeidi and Lorna Aucott and Black, {Alison J.} and Fraser, {William D.} and Reid, {David M.} and Macdonald, {Helen M.}",

note = "{\textcopyright} 2013 Mavroeidi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. This work was funded by the United Kingdom Food Standards Agency (N05062). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. ",

year = "2013",

month = jan,

day = "8",

doi = "10.1371/journal.pone.0053381",

language = "English",

volume = "8",

journal = "PLoS One",

issn = "1932-6203",