Sequence typing confirms that a predominant Listeria monocytogenes clone caused human listeriosis cases and outbreaks in Canada from 1988 to 2010

Stephen J. Knabel, Aleisha Reimer, Bindhu Verghese, Mei Lok, Jennifer Ziegler, Jeffrey Farber, Franco Pagotto, Morag Graham, Celine A. Nadon, Matthew W. Gilmour

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105 Citations (Scopus)


Human listeriosis outbreaks in Canada have been predominantly caused by serotype 1/2a isolates with highly similar pulsedfield gel electrophoresis (PFGE) patterns. Multilocus sequence typing (MLST) and multi-virulence-locus sequence typing (MVLST) each identified a diverse population of Listeria monocytogenes isolates, and within that, both methods had congruent subtypes that substantiated a predominant clone (clonal complex 8; virulence type 59; proposed epidemic clone 5 [ECV]) that has been causing human illness across Canada for more than 2 decades.

Original languageEnglish
Pages (from-to)1748-1751
Number of pages4
JournalJournal of Clinical Microbiology
Issue number5
Publication statusPublished - May 2012

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