Seroepidemiology of group C rotavirus infection in England and Wales

Miren Iturriza-Gómara, Ian Clarke, Ulrich Desselberger, David Brown, Daniel Thomas, Jim Gray

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A total of 3199 serum samples collected in 1993--1994 from two population cohorts from England and Wales were tested for the prevalence of IgG antibodies specifically directed against group C rotavirus VP6. Seroprevalence was 39% (95% confidence intervals: 37.0-40.4%). Seroprevalence was highest (46.0%) in the oldest age group (61-70 years of age). Infection with group C rotaviruses occurred at an earlier age and with higher incidence in rural than in urban populations. These results may suggest transmission from animals to humans, however further work is required to identify the reservoir of group C rotavirus for human infection.
Original languageEnglish
Pages (from-to)589-595
Number of pages7
JournalEuropean Journal of Epidemiology
Issue number6
Publication statusPublished - 2004

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