Sesquiterpenoids with Anti-MDR Staphylococcus aureus activities from Ferula ferulioides

Tao Liu, Shuangying Wang, Lili Xu, Wei Fu, Simon Gibbons, Qing Mu

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Seven new sesquiterpenoids together with 21 known sesquiterpenoid derivatives were isolated from the medicinal plant Ferula ferulioides (Steud.) Korovin. Their structures were elucidated by comprehensive spectroscopic analyses and chemical transformations. The isolated compounds were evaluated for their antibacterial activities against a panel of bacteria including multidrug-resistant (MDR) and methicillin-resistant Staphylococcus aureus (MRSA), displaying minimum inhibitory concentration (MIC) values in the range of 0.5-128 mg/l.
Original languageEnglish
Pages (from-to)599-614
Number of pages16
JournalChemistry and Biodiversity
Volume12
Issue number4
Early online date16 Apr 2015
DOIs
Publication statusPublished - Apr 2015

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