Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis

Matthew Rutter; Brian Saunders; Kay Wilkinson; Steve Rumbles; Gillian Schofield; Michael Kamm; Christopher Williams; Ashley Price; Ian Talbot; Alastair Forbes

doi:10.1053/j.gastro.2003.11.010

Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis

Matthew Rutter, Brian Saunders, Kay Wilkinson, Steve Rumbles, Gillian Schofield, Michael Kamm, Christopher Williams, Ashley Price, Ian Talbot, Alastair Forbes

Research output: Contribution to journal › Article › peer-review

1078 Citations (SciVal)

Abstract

Patients with ulcerative colitis are at increased risk of colorectal cancer. It is widely believed that this is secondary to colonic inflammation. However, the severity of colonic inflammation has never been shown to be a risk factor.

Original language	English
Pages (from-to)	451-459
Number of pages	9
Journal	Gastroenterology
Volume	126
Issue number	2
DOIs	https://doi.org/10.1053/j.gastro.2003.11.010
Publication status	Published - Feb 2004

Keywords

Adolescent
Adult
Case-Control Studies
Child
Colitis, Ulcerative
Colonoscopy
Colorectal Neoplasms
Cytoprotection
Female
Humans
Male
Mesalamine
Middle Aged
Multivariate Analysis
Odds Ratio
Risk Factors
Severity of Illness Index
Smoking
Sulfasalazine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1053/j.gastro.2003.11.010

Cite this

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title = "Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis",

abstract = "Patients with ulcerative colitis are at increased risk of colorectal cancer. It is widely believed that this is secondary to colonic inflammation. However, the severity of colonic inflammation has never been shown to be a risk factor.",

keywords = "Adolescent, Adult, Case-Control Studies, Child, Colitis, Ulcerative, Colonoscopy, Colorectal Neoplasms, Cytoprotection, Female, Humans, Male, Mesalamine, Middle Aged, Multivariate Analysis, Odds Ratio, Risk Factors, Severity of Illness Index, Smoking, Sulfasalazine",

author = "Matthew Rutter and Brian Saunders and Kay Wilkinson and Steve Rumbles and Gillian Schofield and Michael Kamm and Christopher Williams and Ashley Price and Ian Talbot and Alastair Forbes",

year = "2004",

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language = "English",

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pages = "451--459",

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T1 - Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis

AU - Rutter, Matthew

AU - Saunders, Brian

AU - Wilkinson, Kay

AU - Rumbles, Steve

AU - Schofield, Gillian

AU - Kamm, Michael

AU - Williams, Christopher

AU - Price, Ashley

AU - Talbot, Ian

AU - Forbes, Alastair

PY - 2004/2

Y1 - 2004/2

N2 - Patients with ulcerative colitis are at increased risk of colorectal cancer. It is widely believed that this is secondary to colonic inflammation. However, the severity of colonic inflammation has never been shown to be a risk factor.

AB - Patients with ulcerative colitis are at increased risk of colorectal cancer. It is widely believed that this is secondary to colonic inflammation. However, the severity of colonic inflammation has never been shown to be a risk factor.

KW - Adolescent

KW - Adult

KW - Case-Control Studies

KW - Child

KW - Colitis, Ulcerative

KW - Colonoscopy

KW - Colorectal Neoplasms

KW - Cytoprotection

KW - Female

KW - Humans

KW - Male

KW - Mesalamine

KW - Middle Aged

KW - Multivariate Analysis

KW - Odds Ratio

KW - Risk Factors

KW - Severity of Illness Index

KW - Smoking

KW - Sulfasalazine

U2 - 10.1053/j.gastro.2003.11.010

DO - 10.1053/j.gastro.2003.11.010

M3 - Article

C2 - 14762782

VL - 126

SP - 451

EP - 459

JO - Gastroenterology

JF - Gastroenterology

SN - 0016-5085

IS - 2

ER -